Changes in the mechanical properties of fibroblasts during spreading: a micromanipulation study
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Stem cell use in bladder tissue engineering is a recently addressed area of investigation that has generated excitement as a novel way to restore and regenerate lost or damaged urinary bladder tissue. The remodelling of smooth muscle plays a significant ro ...
Muscle degenerative disorders, such as Duchenne muscular dystrophy, have a profound impact on the quality of life and survival of patients. Transplantation of myoblasts to restore muscle function has been discouraging since these cells die and don't migrat ...
An active implantable chemico-rheological sensor including control electronics, a Digital Signal Processor (DSP) and an RF transceiver has been demonstrated. The ultra-low power system architecture achieves an energy per viscosity measurement of only 16.6m ...
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Most tissue engineering approaches include the delivery of reparative cells to a damaged host tissue. Generally these cells are sought to be of a stem cell character since they retain a high potential for proliferation and differentiation into diverse phen ...
According to the last WHO numbers, cardiac diseases remain the first cause of death in the world. Cell therapy represents a promising approach to restore heart function. Cardiac derived adherent proliferation (CAP) cells were shown to support the heart reg ...
We investigated the feasibility of a concentric rotational microviscometer which is actuated remotely. This type of sensor might find application in vivo as a passive implant. The heart of the sensor is a cylindrical rotor, actuated from a distance of up t ...
Alginate gel formation on-chip is presented in the first part of this thesis. The technique allows immobilization, and release, of biological cells on-chip. Furthermore, via layer by layer deposition, a locally heterogeneous environment can be generated at ...
The mechanical response of the periodontal ligament (PDL) is complex. This tissue responds as a hyperelastic solid when pulled in tension while demonstrating a viscous behavior under compression. This intricacy is reflected in the tissue's morphology, whic ...
This unit describes a protocol for the isolation of cells from murine embryonic stem cells with hematopoietic stem cell activity, defined by the ability to reconstitute, long term, multiple lineages of the hematopoietic system of lethally irradiated mice. ...
Shear thickening fluids (STF) demonstrate the ability to simultaneously stiffen and increase their damping capacity above a critical shear strain, which depends on the particle concentration and aspect ratio in the STF. The present work considers two types ...