Cells in 3D matrices under interstitial flow: Effects of extracellular matrix alignment on cell shear stress and drag forces
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Interstitial fluid flow has been shown to affect the organization and behavior of cells in 3D environments in vivo and in vitro, yet the forces driving such responses are not clear. Due to the complex architecture of the extracellular matrix (ECM) and the ...
Dynamic stresses that are present in all living tissues drive small fluid flows, called interstitial flows, through the extracellular matrix. Interstitial flow not only helps to transport nutrients throughout the tissue, but also has important roles in tis ...
The objective of this review is to examine how the concept of plasticity is used in geophysical fluid dynamics. Rapid mass movements such as snow avalanches or debris flows involve slurries of solid particles (ice, boulder, clay, etc.) within an interstiti ...
Experiments on vortex shedding from a cylinder placed in uniform flows of low concentration polymer solutions are reported for Reynolds numbers from 50 to 150. The fluids used were aqueous solutions of polyethylene oxide (PEO) and rheological characterizat ...
The properties of the cluster HenV, an iron vacancy with an increasing number of He atoms, is studied with molecular statics and molecular dynamics simulations. A study of the binding energy of the self-interstitial atom (SIA) and the He, shows that from n ...
This thesis is intended to contribute to the field of biomechanics of growth and remodeling of arteries. The work focuses particularly on growth and remodeling caused by sustained hypertension, increased blood flow, and ageing. A structure-based constituti ...
The study considers the prediction of the main flow parameters of adiabatic annular two-phase flows, focusing in particular on the void fraction. Recently developed models to predict the entrained liquid fraction, the wall shear stress and the velocity pro ...
Interstitial fluid flow, critical for macromolecular transport, was recently shown to drive fibroblast differentiation and perpendicular cell and matrix alignment in 3D collagen cultures. Here we explore the mechanisms underlying this flow-induced cell and ...
The design of timber rip shells confronts the engineer with major uncertainties during the planning process. The consideration of the elastic compound cross section during structural analysis of curved members by means of conventional calculation methods i ...
Shear flows have a profound influence on turbulence-driven transport in tokamaks. The introduction of arbitrary initial flow profiles into the code ORB5 [Jolliet et al., Comput. Phys. Commun. 177, 409 (2007)] allows the convenient study of how flows on all ...