High-speed photography of compressed human trabecular bone correlates whitening to microscopic damage
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Purpose. To assess the effect of external mechanical microstimuli of controlled magnitude on the microarchitecture of the peri-implant bone beds in rat tibiae. Materials and Methods. Tibiae of forty rats were fitted with two transcutaneous titanium cylinde ...
After a fracture, fixing a plate to a broken bone can be problematic if the bone suffers of osteoporosis. In order to find a solution to increase bone density around the plate screws, one solution is to insert a drug-delivering bone plug that inhibits bone ...
Reversed shoulder arthroplasty (RSA) is recommended in case of severe muscle deficiency, along with important joint wear. Although having a correct placement of the prosthesis after the operation and a recovery of the mobility, several cases of scapula fra ...
Supercritical carbon dioxide processing of poly--lactide (PLLA)/hydroxyapatite (nHA) nanocomposites was investigated as a means to prepare foams suitable as scaffolds in bone tissue engineering applications. For given foaming parameters, addition of nHA to ...
Osteoporosis is one of the most common skeletal diseases that lead to an accelerated bone loss due to an imbalance in bone turnover. This low bone mass and degraded bone microarchitecture cause a reduction in mechanical properties and an associated increas ...
There is increasing evidence that mechanical stimulation affects the fate of tissue engineering scaffolds. In clinical situations, it is critical to accelerate bone formation inside the scaffold to reduce the recovery time and increase the chance of succes ...
The present work forms part of an ongoing effort at the Laboratory of Polymer and Composite Technology (LTC) to develop novel solvent-free processing methods for next generation resorbable porous scaffolds for bone replacement, based on supercritical carbo ...
The goal of this study was to investigate if the preparation of implantation site has an impact on bone formation inside tissue engineering scaffolds. For this purpose, two different drilling techniques were used to create a hole in distal femurs of rats b ...
Background: The primary stability of cancellous screw is difficult to obtain in bone of compromised quality and failure of screw fixation is common. To overcome this problem, it is proposed to locally deliver bisphosphonate from the screw An in vivo valida ...
A successful bone tissue engineering strategy entails producing bone-scaffold construct with adequate mechanical properties. Apart from the mechanical properties of the scaffold itself, the forming bone inside the scaffold also adds to the strength of the ...