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Novel techniques for high-resolution functional imaging of teabecular bone

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Leptin: cutting the fat off the bone

Johan Auwerx

CONTEXT: Leptin was initially proposed to be the antiobesity hormone. Now it is realised that leptin is more a signal molecule that communicates nutritional status to the brain, and that it is involved in bone formation by having an antiosteogenic action. ...

2003

Colored visualization of shape differences between bones

Daniel Thalmann, Sofiane Sarni, Ik Soo Lim

This article addresses visualization of deformation or shape differences between bones while conventional visualization techniques are often about a single bone such as its 3D reconstruction. Given a pair of bones with a set of corresponding anatomical lan ...

IEEE2003

Colored visualization of shape differences between bones

Daniel Thalmann, Sofiane Sarni, Ik Soo Lim

Institute of Electrical and Electronics Engineers Computer Society2003

Cells and tissue imaging with digital holographic microscopy

Pierre Magistretti, Christian Depeursinge, Tristan Colomb, Etienne Cuche, Frédéric Montfort, Pierre Marquet, Mihaela Marian

The aim of Optical Digital Holography, applied to cells and tissue imaging, is to provide an accurate 3D imaging of biologic materials, down to the microscopic scale. The method has been developed to yield a very precise determination of cells and tissues ...

SPIE2003

Synchrotron radiation Imaging of internal structures in live animals

Giorgio Margaritondo

Ionizing radiation has long been used in medicine since the discovery of X-rays. Diagnostic imaging using synchrotron radiation has been under investigation since Rubenstein et al. reported dual-energy iodine-K-edge subtraction coronary angiography. Recent ...

2002

Mechanical characterization of bone from the tissue down to the lamellar level by means of nanoindentation

Osteoporosis has become an important health and economic problem of our aging western society. This metabolic illness leads to a net bone loss and to a deterioration of trabecular architecture. Motivated by the fact that osteoporosis may also result in a d ...

EPFL2002

Coherent x-rays in the world of nanoscience

Giorgio Margaritondo, Marco Grioni

Coherent x-rays are here! This exciting news is a byproduct of the effort to increase the brightness of synchrotron light sources. We discuss the basic issues concerning x-ray coherence, and some of the applications that are already underway - with particu ...

1998

A constitutive law for trabecular bone

Motivated by applications in orthopaedic surgery, new constitutive laws for trabecular (or spongious) bone are developed in the framework of continuum mechanics, implemented in a mechanical analysis computer program, validated by a number of in vitro exper ...

EPFL1994