Publication

Bronsted Acid Catalyzed Enantioselective Three-Component Reaction Involving the alpha Addition of Isocyanides to Imines

Jieping Zhu
2009
Journal paper

Abstract

That a chiral phosphoric acid is able to catalyze the three-component reaction of aldehydes, anilines, and alpha -isocyanoacetamides, leading to 2-(1-aminoalkyl)-5-aminooxazoles in excellent yields and moderate to good enantioselectivities, was reported. [on SciFinder (R)]

Official source

https://infoscience.epfl.ch/record/158042?ln=en

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