Publication

Synthesis of ring-A-substituted tryptophan by a palladium-catalyzed heteroannulation reaction

Jieping Zhu
2005
Journal paper

Abstract

Coupling of substituted 2-iodoanilines with Me (S)-2-[di(tert-butoxycarbonyl)amino]-5-oxopentanoate, derived from glutamic acid, in DMF in the presence of Pd(OAc)2 and DABCO provides substituted tryptophans in good to excellent yields. [on SciFinder (R)]

Official source

https://infoscience.epfl.ch/record/158110?ln=en

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Synthesis of ring-A-substituted tryptophan by a palladium-catalyzed heteroannulation reaction

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