Synthesis of ring-A-substituted tryptophan by a palladium-catalyzed heteroannulation reaction

Jieping Zhu
2005
Article

Résumé

Coupling of substituted 2-iodoanilines with Me (S)-2-[di(tert-butoxycarbonyl)amino]-5-oxopentanoate, derived from glutamic acid, in DMF in the presence of Pd(OAc)2 and DABCO provides substituted tryptophans in good to excellent yields. [on SciFinder (R)]

Source officielle

https://infoscience.epfl.ch/record/158110?ln=fr

À propos de ce résultat

Cette page est générée automatiquement et peut contenir des informations qui ne sont pas correctes, complètes, à jour ou pertinentes par rapport à votre recherche. Il en va de même pour toutes les autres pages de ce site. Veillez à vérifier les informations auprès des sources officielles de l'EPFL.

Synthesis of ring-A-substituted tryptophan by a palladium-catalyzed heteroannulation reaction

Variants of the gain domain of adhesion g protein-coupled receptors

The Mouse Eugenol Odorant Receptor: Structural and Functional Plasticity of a Broadly Tuned Odorant Binding Pocket

Palladium-Catalyzed, Modular Synthesis of Highly Functionalized Indoles and Tryptophans by Direct Annulation of Substituted o-Haloanilines and Aldehydes

Variants of the gain domain of adhesion g protein-coupled receptors

The Mouse Eugenol Odorant Receptor: Structural and Functional Plasticity of a Broadly Tuned Odorant Binding Pocket

Palladium-Catalyzed, Modular Synthesis of Highly Functionalized Indoles and Tryptophans by Direct Annulation of Substituted o-Haloanilines and Aldehydes