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N-tert-butyloxycarbonyl (Boc) groups can be removed from peptides supported on Rink's amide resin by treatment with trimethylsilyl triflate/2,6-lutidine. This methodol. was illustrated here with syntheses of several peptides, but it is likely to be used more extensively in solid phase syntheses of small mol. libraries. [on SciFinder (R)]
Christian Heinis, Edward Will, Anne Sofie Luise Zarda, Alexander Lund Nielsen, Sevan Mleh Habeshian, Mischa Schüttel, Gontran Sangouard