Publications related to Bone healing induced by local delivery of an engineered parathyroid hormone prodrug

Engineering 3D cell instructive microenvironments by rational assembly of artificial extracellular matrices and cell patterning

Matthias Lütolf, Adrian Ranga, Martin Ehrbar

Engineered artificial microenvironments hold enormous potential as models to study developmental, physiological, pathological, and regenerative processes under highly defined conditions. Such platforms aim at bridging the gap between traditional in vitro 2 ...

2011

The role of MYC in bone and in the hematopoietic stem cell niche

Maike Jaworski

The nuclear protein c-Myc is one of the most potent proto-oncogenes described. Its expression is found to be deregulated in more than 50 percent of human cancers, where it has been shown to control a number of biological processes including driving prolife ...

EPFL2009

Design, fabrication, and characterization of a composite scaffold for bone tissue engineering

Melody Swartz, Alice Anna Tomei, Federica Boschetti

Poly(lactide-co-glycolide) (PLGA) scaffolds have been successfully used in bone tissue engineering, with or without hydroxyapatite (HA) and with a macroporosity given either by simple PLGA sphere packaging and/or by leaching out NaCI. The objective of this ...

Wichtig Editore2008

Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: Systematic modulation of a synthetic cell-responsive PEG-hydrogel

Matthias Lütolf, Jeffrey Alan Hubbell

We show that synthetic three-dimensional (3D) matrix metalloproteinase (MMP)-sensitive poly(ethylene glycol) (PEG)-based hydrogels can direct differentiation of pluripotent cardioprogenitors, using P19 embryonal carcinoma (EC) cells as a model, along a car ...

2008

Plate for matrix-assisted laser desorption ionization mass spectrometry for, e.g. analyzing peptide, has substrate that is covered with light sensitive matrix with light absorber, charge carrier, probe molecule and photo-sensitizer

Hubert Girault, Niels Erik Lion, Christophe Roussel, Liang Qiao

NOVELTY - The plate has electrically conductive substrate (1) that is covered with light sensitive matrix (2). The matrix comprises light absorber, charge carrier, probe molecule and photo-sensitizer (3) arranged to oxidize probe molecule by irradiation of ...

2008

Engineered blood and lymphatic capillaries in 3-D VEGF-fibrin-collagen matrices with interstitial flow

Melody Swartz

In vitro endothelial cell organization into capillaries is a long standing challenge of tissue engineering. We recently showed the utility of low level interstitial flow in guiding the organization of endothelial cells through a 3-D fibrin matrix-containin ...

Wiley-Blackwell2007

Fetal bone cells for tissue engineering

In this thesis, the potential use of fetal bone cells for tissue engineering was evaluated. At first, fetal bone cells were characterized in vitro regarding their proliferation rate, the induction of their osteoblastic phenotype, and their antigenicity. Th ...

EPFL2007

Theroretical and experimental multi-scale study of an artificial bone construct

Luc Blecha

Synthetic bone substitutes are potentially the future gold standard in orthopaedic and traumatologic surgery. The availability of these bone substitutes with different biomechanical properties may well replace autografts in the future as they overcome comp ...

EPFL2007

Efficient trapping of silver cations in a rare gas matrix: Ag3+ in argon

Sylvain Lecoultre, Alexandre Rydlo

Mass selected cations of Ag-clusters are deposited, together with Ar seeded with CO

_2

(or other electron scavengers such as O

_2

, N

_2

O, or CCl

_4

), on a cold substrate, while being flooded with low energy electrons. Optical absorption measurements re ...

2007

Matrix effects on the optical response of silver nanoclusters

Sylvain Lecoultre, Alexandre Rydlo, Fabien Conus

We report absorption spectra for Ag7, Ag9, and Ag11 in an argon matrix grown at a temperature of 28 K and compare them with previous spectra of the same species measured in matrices of argon grown at lower temperatures as well as in neon matrices. We discu ...

2006

Bone healing induced by local delivery of an engineered parathyroid hormone prodrug

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Engineering 3D cell instructive microenvironments by rational assembly of artificial extracellular matrices and cell patterning

The role of MYC in bone and in the hematopoietic stem cell niche

Design, fabrication, and characterization of a composite scaffold for bone tissue engineering

Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: Systematic modulation of a synthetic cell-responsive PEG-hydrogel

Plate for matrix-assisted laser desorption ionization mass spectrometry for, e.g. analyzing peptide, has substrate that is covered with light sensitive matrix with light absorber, charge carrier, probe molecule and photo-sensitizer

Engineered blood and lymphatic capillaries in 3-D VEGF-fibrin-collagen matrices with interstitial flow

Fetal bone cells for tissue engineering

Theroretical and experimental multi-scale study of an artificial bone construct

Efficient trapping of silver cations in a rare gas matrix: Ag3+ in argon

Matrix effects on the optical response of silver nanoclusters

Engineering 3D cell instructive microenvironments by rational assembly of artificial extracellular matrices and cell patterning

The role of MYC in bone and in the hematopoietic stem cell niche

Engineered blood and lymphatic capillaries in 3-D VEGF-fibrin-collagen matrices with interstitial flow

Design, fabrication, and characterization of a composite scaffold for bone tissue engineering

Plate for matrix-assisted laser desorption ionization mass spectrometry for, e.g. analyzing peptide, has substrate that is covered with light sensitive matrix with light absorber, charge carrier, probe molecule and photo-sensitizer

Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: Systematic modulation of a synthetic cell-responsive PEG-hydrogel

Fetal bone cells for tissue engineering

Theroretical and experimental multi-scale study of an artificial bone construct

Efficient trapping of silver cations in a rare gas matrix: Ag3+ in argon

Matrix effects on the optical response of silver nanoclusters