MicrofluidicsMicrofluidics refers to a system that manipulates a small amount of fluids ((10−9 to 10−18 liters) using small channels with sizes ten to hundreds micrometres. It is a multidisciplinary field that involves molecular analysis, biodefence, molecular biology, and microelectronics. It has practical applications in the design of systems that process low volumes of fluids to achieve multiplexing, automation, and high-throughput screening.
Lab-on-a-chipA lab-on-a-chip (LOC) is a device that integrates one or several laboratory functions on a single integrated circuit (commonly called a "chip") of only millimeters to a few square centimeters to achieve automation and high-throughput screening. LOCs can handle extremely small fluid volumes down to less than pico-liters. Lab-on-a-chip devices are a subset of microelectromechanical systems (MEMS) devices and sometimes called "micro total analysis systems" (μTAS). LOCs may use microfluidics, the physics, manipulation and study of minute amounts of fluids.
Organ-on-a-chipAn organ-on-a-chip (OOC) is a multi-channel 3-D microfluidic cell culture, integrated circuit (chip) that simulates the activities, mechanics and physiological response of an entire organ or an organ system. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context.
YeastYeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are estimated to constitute 1% of all described fungal species. Yeasts are unicellular organisms that evolved from multicellular ancestors, with some species having the ability to develop multicellular characteristics by forming strings of connected budding cells known as pseudohyphae or false hyphae.
Yeast extractYeast extracts consist of the cell contents of yeast without the cell walls; they are used as food additives or flavorings, or as nutrients for bacterial culture media. They are often used to create savory flavors and umami taste sensations, and can be found in a large variety of packaged food, including frozen meals, crackers, snack foods, gravy, stock and more. They are rich in B vitamins (but not B12). Yeast extracts and fermented foods contain glutamic acid (free glutamates), an amino acid which adds an umami flavor.
Finitely generated algebraIn mathematics, a finitely generated algebra (also called an algebra of finite type) is a commutative associative algebra A over a field K where there exists a finite set of elements a1,...,an of A such that every element of A can be expressed as a polynomial in a1,...,an, with coefficients in K. Equivalently, there exist elements s.t. the evaluation homomorphism at is surjective; thus, by applying the first isomorphism theorem, . Conversely, for any ideal is a -algebra of finite type, indeed any element of is a polynomial in the cosets with coefficients in .
Field extensionIn mathematics, particularly in algebra, a field extension is a pair of fields such that the operations of K are those of L restricted to K. In this case, L is an extension field of K and K is a subfield of L. For example, under the usual notions of addition and multiplication, the complex numbers are an extension field of the real numbers; the real numbers are a subfield of the complex numbers. Field extensions are fundamental in algebraic number theory, and in the study of polynomial roots through Galois theory, and are widely used in algebraic geometry.
Finitely generated moduleIn mathematics, a finitely generated module is a module that has a finite generating set. A finitely generated module over a ring R may also be called a finite R-module, finite over R, or a module of finite type. Related concepts include finitely cogenerated modules, finitely presented modules, finitely related modules and coherent modules all of which are defined below. Over a Noetherian ring the concepts of finitely generated, finitely presented and coherent modules coincide.
Yeast in winemakingThe role of yeast in winemaking is the most important element that distinguishes wine from fruit juice. In the absence of oxygen, yeast converts the sugars of the fruit into alcohol and carbon dioxide through the process of fermentation. The more sugars in the grapes, the higher the potential alcohol level of the wine if the yeast are allowed to carry out fermentation to dryness. Sometimes winemakers will stop fermentation early in order to leave some residual sugars and sweetness in the wine such as with dessert wines.
Droplet-based microfluidicsDroplet-based microfluidics manipulate discrete volumes of fluids in immiscible phases with low Reynolds number and laminar flow regimes. Interest in droplet-based microfluidics systems has been growing substantially in past decades. Microdroplets offer the feasibility of handling miniature volumes (μl to fl) of fluids conveniently, provide better mixing, encapsulation, sorting, sensing and are suitable for high throughput experiments.
