BurstingBursting, or burst firing, is an extremely diverse general phenomenon of the activation patterns of neurons in the central nervous system and spinal cord where periods of rapid action potential spiking are followed by quiescent periods much longer than typical inter-spike intervals. Bursting is thought to be important in the operation of robust central pattern generators, the transmission of neural codes, and some neuropathologies such as epilepsy.
Single-unit recordingIn neuroscience, single-unit recordings (also, single-neuron recordings) provide a method of measuring the electro-physiological responses of a single neuron using a microelectrode system. When a neuron generates an action potential, the signal propagates down the neuron as a current which flows in and out of the cell through excitable membrane regions in the soma and axon. A microelectrode is inserted into the brain, where it can record the rate of change in voltage with respect to time.
Models of neural computationModels of neural computation are attempts to elucidate, in an abstract and mathematical fashion, the core principles that underlie information processing in biological nervous systems, or functional components thereof. This article aims to provide an overview of the most definitive models of neuro-biological computation as well as the tools commonly used to construct and analyze them.
SynapseIn the nervous system, a synapse is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target effector cell. Synapses are essential to the transmission of nervous impulses from one neuron to another. Neurons are specialized to pass signals to individual target cells, and synapses are the means by which they do so. At a synapse, the plasma membrane of the signal-passing neuron (the presynaptic neuron) comes into close apposition with the membrane of the target (postsynaptic) cell.
Neuronal ensembleA neuronal ensemble is a population of nervous system cells (or cultured neurons) involved in a particular neural computation. The concept of neuronal ensemble dates back to the work of Charles Sherrington who described the functioning of the CNS as the system of reflex arcs, each composed of interconnected excitatory and inhibitory neurons. In Sherrington's scheme, α-motoneurons are the final common path of a number of neural circuits of different complexity: motoneurons integrate a large number of inputs and send their final output to muscles.
G-type main-sequence starA G-type main-sequence star (spectral type: G-V), also often, and imprecisely called a yellow dwarf, or G star, is a main-sequence star (luminosity class V) of spectral type G. Such a star has about 0.9 to 1.1 solar masses and an effective temperature between about 5,300 and 6,000 K. Like other main-sequence stars, a G-type main-sequence star converts the element hydrogen to helium in its core by means of nuclear fusion, but can also fuse helium when hydrogen runs out.
Cortical columnA cortical column is a group of neurons forming a cylindrical structure through the cerebral cortex of the brain perpendicular to the cortical surface. The structure was first identified by Mountcastle in 1957. He later identified minicolumns as the basic units of the neocortex which were arranged into columns. Each contains the same types of neurons, connectivity, and firing properties. Columns are also called hypercolumn, macrocolumn, functional column or sometimes cortical module.
A-type main-sequence starAn A-type main-sequence star (A) or A dwarf star is a main-sequence (hydrogen burning) star of spectral type A and luminosity class (five). These stars have spectra defined by strong hydrogen Balmer absorption lines. They measure between 1.4 and 2.1 solar masses () and have surface temperatures between 7,600 and 10,000 K. Bright and nearby examples are Altair (A7), Sirius A (A1), and Vega (A0). A-type stars do not have convective zones and thus are not expected to harbor magnetic dynamos.
Cerebral cortexThe cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system.
B-type main-sequence starA B-type main-sequence star (B V) is a main-sequence (hydrogen-burning) star of spectral type B and luminosity class V. These stars have from 2 to 16 times the mass of the Sun and surface temperatures between 10,000 and 30,000 K. B-type stars are extremely luminous and blue. Their spectra have strong neutral helium absorption lines, which are most prominent at the B2 subclass, and moderately strong hydrogen lines. Examples include Regulus and Algol A.
