Metabolic pathway and distribution of superparamagnetic iron oxide nanoparticles: in vivo study
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Morphology is an important factor in locomotion. It may guide the control strategies that an animal or a robot uses for efficient locomotion. In this paper we try to understand the locomotion strategies of a lizard with a distinctive feature, the long-tail ...
A major challenge in cancer biology is to monitor and understand cancer metabolism in vivo with the goal of improved diagnosis and perhaps therapy. Because of the complexity of biochemical pathways, tracer methods are required for detecting specific enzyme ...
The engineering of the metabolism requires the building of reliable kinetic models of the metabolic pathways through the integration of the information from heterogeneous data sources. Unfortunately, the quantitative knowledge about fluxes, mechanisms or k ...
A robot properly introduced into an animal group, accepted by the animals, and capable of interacting with them is a very powerful tool for advanced ethological research, particularly in gregarious animals. Moreover, such robots can find an application in ...
Metabolic networks have been studied for decades, and sophisticated computational frameworks are needed to augment experimental approaches to harness these complex networks. BNICE (Biochemical Network Integrated Computational Explorer), a computational app ...
Study of a metabolic network with respect to the sensitivity of the metabolite concentrations and the metabolic fluxes to genetic, biochemical, and environmental variations requires knowledge of the kinetic properties of the enzymes in the network. Experim ...
One of the central problems in metabolic engineering deals with the identification of the "rate limiting steps", i.e. enzymes whose activities one should manipulate towards the achievement of a desirable performance. However, uncertainty about the kinetic ...
Semiconductor quantum dots and superparamagnetic iron oxide nanocrystals have physical properties that are well suited for biomedical imaging. Previously, we have shown that iron oxide nanocrystals embedded within the lipid core of micelles show optimized ...
Neural Metabolism In Vivo strives to offer a comprehensive and fundamental overview of cerebral metabolism by presenting leading-edge in vivo multimodal technology and its application in assessing neural activity, energy metabolism and neurotransmission in ...
In vivo 13C NMR spectroscopy has the unique capability to measure metabolic fluxes noninvasively in the brain. Quantitative measurements of metabolic fluxes require analysis of the 13C labeling time courses obtained experimentally with a metabolic model. T ...