Total synthesisTotal synthesis is the complete chemical synthesis of a complex molecule, often a natural product, from simple, commercially-available precursors. It usually refers to a process not involving the aid of biological processes, which distinguishes it from semisynthesis. Syntheses may sometimes conclude at a precursor with further known synthetic pathways to a target molecule, in which case it is known as a formal synthesis. Total synthesis target molecules can be natural products, medicinally-important active ingredients, known intermediates, or molecules of theoretical interest.
Ring (mathematics)In mathematics, rings are algebraic structures that generalize fields: multiplication need not be commutative and multiplicative inverses need not exist. In other words, a ring is a set equipped with two binary operations satisfying properties analogous to those of addition and multiplication of integers. Ring elements may be numbers such as integers or complex numbers, but they may also be non-numerical objects such as polynomials, square matrices, functions, and power series.
Quotient ringIn ring theory, a branch of abstract algebra, a quotient ring, also known as factor ring, difference ring or residue class ring, is a construction quite similar to the quotient group in group theory and to the quotient space in linear algebra. It is a specific example of a quotient, as viewed from the general setting of universal algebra. Starting with a ring R and a two-sided ideal I in R, a new ring, the quotient ring R / I, is constructed, whose elements are the cosets of I in R subject to special + and ⋅ operations.
Oxidation stateIn chemistry, the oxidation state, or oxidation number, is the hypothetical charge of an atom if all of its bonds to other atoms were fully ionic. It describes the degree of oxidation (loss of electrons) of an atom in a chemical compound. Conceptually, the oxidation state may be positive, negative or zero. While fully ionic bonds are not found in nature, many bonds exhibit strong ionicity, making oxidation state a useful predictor of charge. The oxidation state of an atom does not represent the "real" charge on that atom, or any other actual atomic property.
Natural productA natural product is a natural compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life. Natural products can also be prepared by chemical synthesis (both semisynthesis and total synthesis) and have played a central role in the development of the field of organic chemistry by providing challenging synthetic targets.
Ordered ringIn abstract algebra, an ordered ring is a (usually commutative) ring R with a total order ≤ such that for all a, b, and c in R: if a ≤ b then a + c ≤ b + c. if 0 ≤ a and 0 ≤ b then 0 ≤ ab. Ordered rings are familiar from arithmetic. Examples include the integers, the rationals and the real numbers. (The rationals and reals in fact form ordered fields.) The complex numbers, in contrast, do not form an ordered ring or field, because there is no inherent order relationship between the elements 1 and i.
Noetherian ringIn mathematics, a Noetherian ring is a ring that satisfies the ascending chain condition on left and right ideals; if the chain condition is satisfied only for left ideals or for right ideals, then the ring is said left-Noetherian or right-Noetherian respectively. That is, every increasing sequence of left (or right) ideals has a largest element; that is, there exists an n such that: Equivalently, a ring is left-Noetherian (resp. right-Noetherian) if every left ideal (resp. right-ideal) is finitely generated.
Noncommutative ringIn mathematics, a noncommutative ring is a ring whose multiplication is not commutative; that is, there exist a and b in the ring such that ab and ba are different. Equivalently, a noncommutative ring is a ring that is not a commutative ring. Noncommutative algebra is the part of ring theory devoted to study of properties of the noncommutative rings, including the properties that apply also to commutative rings. Sometimes the term noncommutative ring is used instead of ring to refer to an unspecified ring which is not necessarily commutative, and hence may be commutative.
Rings of SaturnThe rings of Saturn are the most extensive ring system of any planet in the Solar System. They consist of countless small particles, ranging in size from micrometers to meters, that orbit around Saturn. The ring particles are made almost entirely of water ice, with a trace component of rocky material. There is still no consensus as to their mechanism of formation. Although theoretical models indicated that the rings were likely to have formed early in the Solar System's history, newer data from Cassini suggested they formed relatively late.
Medicinal chemistryMedicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs, their biological properties, and their quantitative structure-activity relationships (QSAR).
