Elucidating the mechanisms of paclitaxel-loaded-nanoparticle-induced immune response
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During the last 30 years of psychoneuroimmunology research the intense bi-directional communication between the central nervous system (CNS) and the immune system has been demonstrated in studies on the interaction between the nervous-endocrine-immune syst ...
In the present study, we have assessed the effect of the peroxisome proliferator-activated receptor-alpha (PPARalpha) agonist fenofibrate on allergen-induced airway inflammation and immune response. C57BL/6 or PPARalpha knock-out (PPARalpha(-/-)) mice were ...
Interleukin 21 (IL-21) is a member of the common gamma-chain family of cytokines, which influence a broad spectrum of immunologic responses. A number of studies have examined the function of IL-21, but its specific role in Th1/Th2-cell differentiation and ...
We investigate the usability of the Artificial Immune Systems (AIS) approach for solving selected problems in computer networks. Artificial immune systems are created by using the concepts and algorithms inspired by the theory of how the Human Immune Syste ...
We found an inconsistency between biological data and some of the initial conditions of the mathematical model of tumor growth in ``A Validated Mathematical Model of Cell- Mediated Immune Response to Tumor Growth'' dePillis2005. We show that correcting thi ...
Mycolactone is a polyketide toxin produced by Mycobacterium ulcerans (Mu), the causative agent of the skin disease Buruli ulcer (BU). Surprisingly, infected tissues lack inflammatory infiltrates. Structural similarities between mycolactone and immunosuppre ...
This paper presents a case study of different fault-tolerant architectures. The emphasis is on the silicon realization. A 128bit AES cryptographic core has been designed and fabricated as a main topology on which the fault-tolerant architectures have been ...
Artificial immune systems (AIS) use the concepts and algorithms inspired by the theory of how the human immune system works. This document presents the design and initial evaluation of a new artificial immune system for collaborative spam filtering. Collab ...
This paper presents a new approach for monitoring and estimating device reliability of nanometer-scale devices prior to fabrication. A four-layer architecture exhibiting a large immunity to permanent as well as random failures is used. A complete tool for ...
In naive individuals, the administration of bacterial lipopolysaccharide (LPS) provokes a rapid systemic increase in pro-inflammatory cytokines such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta and IL-6, inducing an acute phase response inc ...