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How to Measure Cortical Folding from MR Images: a Step-by-Step Tutorial to Compute Local Gyrification Index

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Encephalization quotient

Encephalization quotient (EQ), encephalization level (EL), or just encephalization is a relative brain size measure that is defined as the ratio between observed and predicted brain mass for an animal of a given size, based on nonlinear regression on a range of reference species. It has been used as a proxy for intelligence and thus as a possible way of comparing the intelligence levels of different species. For this purpose, it is a more refined measurement than the raw brain-to-body mass ratio, as it takes into account allometric effects.

Entorhinal cortex

The entorhinal cortex (EC) is an area of the brain's allocortex, located in the medial temporal lobe, whose functions include being a widespread network hub for memory, navigation, and the perception of time. The EC is the main interface between the hippocampus and neocortex. The EC-hippocampus system plays an important role in declarative (autobiographical/episodic/semantic) memories and in particular spatial memories including memory formation, memory consolidation, and memory optimization in sleep.

Special senses

In medicine and anatomy, the special senses are the senses that have specialized organs devoted to them: vision (the eye) hearing and balance (the ear, which includes the auditory system and vestibular system) smell (the nose) taste (the tongue) The distinction between special and general senses is used to classify nerve fibers running to and from the central nervous system – information from special senses is carried in special somatic afferents and special visceral afferents.

Proportionality (mathematics)

In mathematics, two sequences of numbers, often experimental data, are proportional or directly proportional if their corresponding elements have a constant ratio. The ratio is called coefficient of proportionality (or proportionality constant) and its reciprocal is known as constant of normalization (or normalizing constant). Two sequences are inversely proportional if corresponding elements have a constant product, also called the coefficient of proportionality.