Novel use of X-ray micro computed tomography to image rat sciatic nerve and integration into scaffold
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The interest in new materials and their application in the neuroscience are growing incredibly fast. Current research interests are increasingly focusing on new artificial materials and their direct effects on the central nervous systems so that it would b ...
The treatment of disorders of the nervous system poses a major clinical challenge. Development of neuromodulation (i.e., interfacing electronics to nervous tissue to modulate its function) has provided patients with neuronal-related deficits a new tool to ...
The aim of a European project Nephron+ is design of a wearable artificial kidney device (WAKD). This paper is focused on design of the corresponding ultralow-hemolysis continuous-operation blood pump. Accurate specifications and operating principle of the ...
This book offers a mathematical update of the state of the art of the research in the field of mathematical and numerical models of the circulatory system. It is structured into different chapters, written by outstanding experts in the field. Many fundamen ...
In this contribution we present our work on filtration of plasma from whole blood in a polymer-based microfluidic system. The absorption of pathogens was found to be low; therefore our system is valid for clinical trials. The blood filtration element is ca ...
Gold nanoparticles (GNPs) are promising tools as drug delivery devices. However, upon intravenous injection, they aggregate and are rapidly eliminated from the systemic circulation by macrophages in the reticuloendothelial system, resulting in relatively s ...
Cardiovascular diseases have a major impact in Western countries. Mathematical models and numerical simulations can help the understanding of physiological and pathological processes, complementing the information provided to medical doctors by medical ima ...
We discuss in this thesis the numerical approximation of fluid-structure interaction (FSI) problems with a particular concern (albeit not exclusive) on hemodynamics applications. Firstly, we model the blood as an incompressible fluid and the artery wall as ...
Background and Objectives Microparticles (MPs) are small phospholipid vesicles of less than 1 mu m, shed in blood flow by various cell types. These MPs are involved in several biological processes and diseases. MPs have also been detected in blood products ...
In clinical diagnostics, the fluidic part for sample-preparation should not absorb any of the substances of interest. In this study, the absorption of 4 different interleukins was investigated in a newly developed microfluidic blood filtration element (BFE ...