Statistical Study of the Unfolding of Multimodular Proteins and their Energy Landscape by Atomic Force Microscopy
Graph Chatbot
Chat with Graph Search
Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.
DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.
The aim of this thesis was to explore the statistical physics and the mechanical properties of individual biomolecules, to study their interactions, and to develop new techniques based on atomic force microscopy (AFM). First, we exploit the high resolution ...
Inductive magnetic sensors are widely used for plasma equilibrium reconstruction and control. However, their measurements involve electronic integration and can therefore experience drift leading to inaccurate plasma positioning. For this reason, we have s ...
We are fabricating a bulk-micromachined micromirror device for laser pulse shaping applications on femtosecond time scales. An array of micromirrors is used to individually retard or diminish certain laser frequencies spanning from the UV to the near-infra ...
The modulation spectrum is an efficient representation for describing dynamic information in signals. In this work we investigate how to exploit different elements of the modulation spectrum for extraction of information in automatic recognition of speech ...
Long double stranded DNA (DsDNA) and single stranded DNA (ssDNA) molecules were studied by direct imaging with the Atomic Force Microscope (AFM) in order to determine their scaling properties, exponents, distributions and persistence length in the frame wo ...
This paper investigates the combination of evidence coming from different frequency channels obtained filtering the speech signal at different auditory and modulation frequencies. In our previous work \cite{icassp2008}, we showed that combination of classi ...
We use a single molecule atomic force spectroscopy combined with the steered molecular dynamics simulation to determine a mechanical behavior of neural cell adhesion protein contactin during its unfolding. Force curves typical for modular proteins were obs ...
The thesis presents the development of a custom made atomic force microscope (AFM) conceived to image biological molecules at low temperatures in ultrahigh vacuum conditions, and its application to DNA single molecule studies. Starting from a first prototy ...
This paper investigates the combination of evidence coming from different frequency channels obtained filtering the speech signal at different auditory and modulation frequencies. In our previous work \cite{icassp2008} ...
The fracture resistance of biomineralized tissues such as bone, dentin, and abalone is greatly enhanced through the nanoscale interactions of stiff inorganic mineral components with soft organic adhesive components. A proper understanding of the interactio ...
