Publication

Use of constant denaturant capillary electrophoresis of pooled blood samples to identify single-nucleotide polymorphisms in the genes (Scnn1a and Scnn1b) encoding the alpha and beta subunits of the epithelial sodium channel

Stephan Morgenthaler, Murielle Bochud
2002
Journal paper

Abstract

The epithelial sodium channel (ENaC) is composed of three homologous subunits: alpha, beta, and gamma. Mutations in the Scnn1b and Scnn1g genes, which encode the beta and the gamma subunits of ENaC, cause a severe form of hypertension (Liddle syndrome). The contribution of genetic variants within the Scnn1a gene, which codes for the alpha subunit, has not been investigated.

Official source

https://infoscience.epfl.ch/record/182167?ln=en

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Use of constant denaturant capillary electrophoresis of pooled blood samples to identify single-nucleotide polymorphisms in the genes (Scnn1a and Scnn1b) encoding the alpha and beta subunits of the epithelial sodium channel

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Reprogramming G Protein-Coupled Receptor Structure, Function And Signaling By Computational Design

Reprogramming G Protein-Coupled Receptor Structure, Function And Signaling By Computational Design