Multiplexed surface micropatterning of proteins with a pressure-modulated microfluidic button-membrane
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The physiological properties of cells are typically investigated in ensembles yielding averaged data that mask heterogeneities present in any cell population. Single-cell analysis techniques based on microfluidic "lab on a chip" (LOC) devices have recently ...
Research on microfluidic devices for biological analysis has progressed sufficiently to be developed into point-of-care diagnostics products. The goal of this thesis is to improve multiple aspects of capillary-driven microfluidic devices. In particular, th ...
Contamination with arsenic is a recurring problem in both industrialized and developing countries. Drinking water supplies for large populations can have concentrations much higher than the permissible levels (for most European countries and the United Sta ...
Microfluidic technology has revolutionized the control of flows at small scales giving rise to new possibilities for assembling complex structures on the microscale. We analyze different possible algorithms for assembling arbitrary structures, and demonstr ...
We report on a high-efficiency and self-priming active-valve micropump consisting of a microfluidic chamber structure in glass that is assembled with a polydimethylsiloxane (PDMS) elastic sheet. The latter comprises two valving membranes and a central pump ...
A microfluidic platform for magnetic bead translocation is introduced, consisting of microfabricated magnetic devices. Each magnetic device was constructed of embedded actuation microcoil array in various designs, which enable efficient magnetic beads and ...
Separation of functional magnetic particles or magnetically labeled entities is a key feature for bioanalytical or biomedical applications and therefore also an important component of lab-on-a-chip devices for biological applications. We present a novel in ...
Separation of functional magnetic particles or magnetically labeled entities is a key feature for bioanalytical or biomedical applications and therefore also an important component of lab-on-a-chip devices for biological applications. We present a novel in ...
We present a new method for three-dimensional (3D) magnetic focusing of magnetic microparticles in a microfluidic system. On-chip magnetic particle manipulation in themicrochannel is achieved by a high-gradientmagnetic field generated by means of a microma ...
We introduce a novel tuning mechanism based on pressure actuating force, which can enable a broad spectrum of tunable elastomeric optofluidic devices. Thanks to the flexibility of the Polydimethylsiloxane (PDMS) material, the local deformation inside PDMS ...
Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2010