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Telomerase Inhibitors from Cyanobacteria: Isolation and Synthesis of Sulfoquinovosyl Diacylglycerols from

Related publications (35)

One- and Two-Dimensional High-Resolution NMR from Flat Surfaces

David Lyndon Emsley, Aaron James Rossini, Brennan James Walder

Determining atomic-level characteristics of molecules on two-dimensional surfaces is one of the fundamental challenges in chemistry. High-resolution nuclear magnetic resonance (NMR) could deliver rich structural information, but its application to two-dime ...

AMER CHEMICAL SOC2019

F-19 Magic Angle Spinning Dynamic Nuclear Polarization Enhanced NMR Spectroscopy

David Lyndon Emsley, Dominik Józef Kubicki, Moreno Lelli, Jasmine Viger-Gravel, Claudia Esther Avalos, David Benjamin Roger Antoine Gajan

The introduction of high-frequency, high-power microwave sources, tailored biradicals, and low-temperature magic angle spinning (MAS) probes has led to a rapid development of hyperpolarization strategies for solids and frozen solutions, leading to large ga ...

WILEY-V C H VERLAG GMBH2019

Nuclear overhauser spectroscopy of chiral CHD methylene groups

Geoffrey Bodenhausen, Fabien Ferrage

Nuclear magnetic resonance spectroscopy (NMR) can provide a great deal of information about structure and dynamics of biomolecules. The quality of an NMR structure strongly depends on the number of experimental observables and on their accurate conversion ...

Springer Verlag2016

High-resolution NMR of hydrogen in organic solids by DNP enhanced natural abundance deuterium spectroscopy

David Lyndon Emsley, Aaron James Rossini, Judith Schlagnitweit

We demonstrate that high field (9.4T) dynamic nuclear polarization (DNP) at cryogenic (similar to 100 K) sample temperatures enables the rapid acquisition of natural abundance H-1-H-2 cross-polarization magic angle spinning (CPMAS) solid-state NMR spectra ...

Academic Press Inc Elsevier Science2015

Sensitivity improvement during heteronuclear spin decoupling in solid-state nuclear magnetic resonance experiments at high spinning frequencies and moderate radio-frequency amplitudes

Geoffrey Bodenhausen

Searching for optimal conditions during one- and multi-dimensional solid-state NMR experiments in high static fields may require spinning the sample at frequencies above 40 kHz. This implies challenging requirements for heteronuclear spin decoupling. We ha ...

Elsevier2014

Decoupling of Magnetic Resonance Signals in Time and Frequency Domain

Nuclear magnetic resonance (NMR) was discovered in the first half of the 20th century. Today, neither analytical chemistry without NMR spectroscopy nor medical diagnostics without magnetic resonance imaging (MRI) could be imagined. A magnetic resonance sig ...

EPFL2013

Dynamic Studies through Control of Relaxation in NMR Spectroscopy

Nicola Salvi

In numerous biological processes that constitute the base of living organisms, protein function is fundamentally related to internal dynamics occurring on μs-ms time scales that can give rise to chemical exchange contributions to relaxation. In a heteronuc ...

EPFL2013

Fast and shift-insensitive similarity comparisons of NMR using a tree-representation of spectra

Luc Patiny, Julien Wist

An efficient method to extract and store information from NMR spectra is proposed that is suitable for comparison and construction of a search engine. This method based on trees doesn't require any peak picking or any pre-treatment of the data and is found ...

Elsevier Science Bv2013

Improving Sensitivity in Solid State NMR

Sensitivity in Nuclear Magnetic Resonance (NMR), especially in solid-state NMR, has always been a challenging and important issue and thus a motivation for new developments. The magnetic field B0, the gyromagnetic ratios of the observed nuclei, as well as ...

EPFL2012

Extending Timescales and Narrowing Linewidths in NMR

Geoffrey Bodenhausen, Aurélien Bornet, Pascal Miéville, Sami Jannin, Diego Carnevale, Paul Romeo Vasos, Simone Ulzega, Marc Anthony Caporini, Nicola Salvi, Martial Rey

Among the different fields of research in nuclear magnetic resonance (NMR) which are currently investigated in the Laboratory of Biomolecular Magnetic Resonance (LRMB), two subjects that are closely related to each other are presented in this article. On t ...

Schweizerische Chemische Gesellschaft2011

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