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Vascular effects induced by anti-VEGF agents in the CAM model: Effect of the DMSO

Related publications (33)

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Transient State Monitoring by Total Internal Reflection Fluorescence Microscopy

Theo Lasser, Thiemo Spielmann

Triplet, photo-oxidized and other photoinduced, long-lived states of fluorophores are sensitive to the local environment and thus attractive for microenvironmental imaging purposes. In this work, we introduce an approach where these states are monitored in ...

2010

Photoactivatable Probes for Protein Labeling

Sambashiva Banala

Over the last decade, several protein tags have been developed for the specific and covalent labeling of fusion proteins with small organic probes. Among them, SNAP-tag has been used in many applications such as live cell imaging, protein microarrays and t ...

EPFL2010

Quantitative single-molecule imaging by confocal laser scanning microscopy

A new approach to quantitative single-molecule imaging by confocal laser scanning microscopy (CLSM) is presented. it relies on fluorescence intensity distribution to analyze the molecular occurrence statistics captured by digital imaging and enables direct ...

2008

c-myc in the hematopoietic lineage is crucial for its angiogenic function in the mouse embryo

The c-myc proto-oncogene, which is crucial for the progression of many human cancers, has been implicated in key cellular processes in diverse cell types, including endothelial cells that line the blood vessels and are critical for angiogenesis. The de nov ...

2008

Triplet imaging contrast by modulated excitation

Theo Lasser, Marcel Leutenegger, Boris Hinz, Thiemo Spielmann

A novel imaging method employing the different kinetics of the energetic states of fluorescent markers is presented, where the contrast depends on the triplet kinetics. An attractive feature of triplet states is their long lifetime, rendering them highly s ...

2008

Printing color images visible under uv light on security documents and valuable articles

Roger Hersch, Sylvain Chosson, Philipp Donzé

In the present invention, we propose a method of creating fluorescent color images visible under UV light. It relies on the new colorants that can be achieved by superposing ink dots, possibly at a reduced size, in order to avoid quenching effects. It also ...

2008

Thrombosis efficacy induced by photodynamic therapy using different photosensitizers

Bernadette Pegaz-Toquet

Various human pathologies, such as cancers or, notably, exudative age-related macular degeneration (AMD), are characterized by an abnormal vascular proliferation (angiogenesis), which in the case of this type of AMD, can rapidly lead to blindness if no cou ...

EPFL2007

Single molecule detection on surfaces

Marcel Leutenegger

Monitoring biological relevant reactions on the single molecule level based on fluorescence spectroscopy techniques has become one of the most promising approaches for understanding a variety of phenomena in biophysics, biochemistry and life science. By ap ...

EPFL2007

The Colored Revolution of Bioimaging

Michaël Unser, Cédric René Jean Vonesch, François Aguet

With the recent development of fluorescent probes and new high-resolution microscopes, biological imaging has entered a new era and is presently having a profound impact on the way research is being conducted in the life sciences. Biologists have come to d ...

IEEE2006

Essential role of endothelial Notch1 in angiogenesis

Freddy Radtke

BACKGROUND: Notch signaling influences binary cell fate decisions in a variety of tissues. The Notch1 receptor is widely expressed during embryogenesis and is essential for embryonic development. Loss of global Notch1 function results in early embryonic le ...

2005