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Crossed fiber optic Bessel beams for curvilinear optofluidic transport of dielectric particles

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We report on the first experimental demonstration of resonant optical trapping of dielectric particles in a two-dimensional hollow photonic crystal cavity. The cavities are implemented in an optofluidic chip consisting of a silicon-on-insulator substrate a ...

Spie-Int Soc Optical Engineering2013

Microfluidic integrated hollow photonic crystal cavities for single particle and resonant field interaction

Romuald Houdré, Nicolas Maxime André Descharmes, Ulagalandha Perumal Dharanipathy, Zhaolu Diao

A microfluidic-integrated single particle sensor based on hollow photonic crystal cavities is reported. The interaction relies on the reversible resonance frequency shift induced by a dielectric particle near the cavity. ...

Ieee2012

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Microfluidic technology has been successfully applied to isolate very rare tumor-derived epithelial cells (circulating tumor cells, CTCs) from blood with relatively high yield and purity, opening up exciting prospects for early detection of cancer. However ...

2012

Optofluidic differential spectroscopy for absorbance detection of sub-nanolitre liquid samples

Wuzhou Song, Jianhang Yang

We present a novel optofluidic differential method for carrying out absorbance spectroscopy of subnanolitre volumes of liquid samples on a microfluidic chip. Due to the reduction of liquid volume, the absorbance detection in microfluidics is often hindered ...

Royal Society of Chemistry2012

Optical Trapping in Microfluidic Channels for Functional and Chemical Analysis of Single Cells

Michael Werner

The physiological properties of cells are typically investigated in ensembles yielding averaged data that mask heterogeneities present in any cell population. Single-cell analysis techniques based on microfluidic "lab on a chip" (LOC) devices have recently ...

EPFL2011

Magnetic particle dosing and size separation in a microfluidic channel

Martinus Gijs, Thomas Lehnert, Yves Moser, Rana Afshar Ghasemlouy

Separation of functional magnetic particles or magnetically labeled entities is a key feature for bioanalytical or biomedical applications and therefore also an important component of lab-on-a-chip devices for biological applications. We present a novel in ...

2011

Magnetic particle dosing and size separation in a microfluidic channel

Martinus Gijs, Thomas Lehnert, Yves Moser, Rana Afshar Ghasemlouy

2011

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We present an optical trapping system combining individually addressable multiple laser traps with fluorescence spectroscopy. An in-line set of 64 near-IR laser diodes is used to create a line of individually addressable traps inside a microfluidic chip. T ...

Optical Society of America2011

Three-Dimensional Magnetic Focusing of Superparamagnetic Beads for On-Chip Agglutination Assays

Martinus Gijs, Thomas Lehnert, Yves Moser, Rana Afshar Ghasemlouy

We present a new method for three-dimensional (3D) magnetic focusing of magnetic microparticles in a microfluidic system. On-chip magnetic particle manipulation in themicrochannel is achieved by a high-gradientmagnetic field generated by means of a microma ...

2011

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We might be at the turning point where research in microfluidics undertaken in academia and industrial research laboratories, and substantially sponsored by public grants, may provide a range of portable and networked diagnostic devices. In this Progress R ...

Wiley-Blackwell2011