Explicitly parallel instruction computingExplicitly parallel instruction computing (EPIC) is a term coined in 1997 by the HP–Intel alliance to describe a computing paradigm that researchers had been investigating since the early 1980s. This paradigm is also called Independence architectures. It was the basis for Intel and HP development of the Intel Itanium architecture, and HP later asserted that "EPIC" was merely an old term for the Itanium architecture. EPIC permits microprocessors to execute software instructions in parallel by using the compiler, rather than complex on-die circuitry, to control parallel instruction execution.
Gene predictionIn computational biology, gene prediction or gene finding refers to the process of identifying the regions of genomic DNA that encode genes. This includes protein-coding genes as well as RNA genes, but may also include prediction of other functional elements such as regulatory regions. Gene finding is one of the first and most important steps in understanding the genome of a species once it has been sequenced. In its earliest days, "gene finding" was based on painstaking experimentation on living cells and organisms.
Instruction-level parallelismInstruction-level parallelism (ILP) is the parallel or simultaneous execution of a sequence of instructions in a computer program. More specifically ILP refers to the average number of instructions run per step of this parallel execution. ILP must not be confused with concurrency. In ILP there is a single specific thread of execution of a process. On the other hand, concurrency involves the assignment of multiple threads to a CPU's core in a strict alternation, or in true parallelism if there are enough CPU cores, ideally one core for each runnable thread.
Program analysisIn computer science, program analysis is the process of automatically analyzing the behavior of computer programs regarding a property such as correctness, robustness, safety and liveness. Program analysis focuses on two major areas: program optimization and program correctness. The first focuses on improving the program’s performance while reducing the resource usage while the latter focuses on ensuring that the program does what it is supposed to do.
Protein–protein interaction predictionProtein–protein interaction prediction is a field combining bioinformatics and structural biology in an attempt to identify and catalog physical interactions between pairs or groups of proteins. Understanding protein–protein interactions is important for the investigation of intracellular signaling pathways, modelling of protein complex structures and for gaining insights into various biochemical processes.
Instruction schedulingIn computer science, instruction scheduling is a compiler optimization used to improve instruction-level parallelism, which improves performance on machines with instruction pipelines. Put more simply, it tries to do the following without changing the meaning of the code: Avoid pipeline stalls by rearranging the order of instructions. Avoid illegal or semantically ambiguous operations (typically involving subtle instruction pipeline timing issues or non-interlocked resources).
Protein structure predictionProtein structure prediction is the inference of the three-dimensional structure of a protein from its amino acid sequence—that is, the prediction of its secondary and tertiary structure from primary structure. Structure prediction is different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by computational biology; and it is important in medicine (for example, in drug design) and biotechnology (for example, in the design of novel enzymes).
Static program analysisIn computer science, static program analysis (or static analysis) is the analysis of computer programs performed without executing them, in contrast with dynamic program analysis, which is performed on programs during their execution. The term is usually applied to analysis performed by an automated tool, with human analysis typically being called "program understanding", program comprehension, or code review. In the last of these, software inspection and software walkthroughs are also used.
Out-of-order executionIn computer engineering, out-of-order execution (or more formally dynamic execution) is a paradigm used in most high-performance central processing units to make use of instruction cycles that would otherwise be wasted. In this paradigm, a processor executes instructions in an order governed by the availability of input data and execution units, rather than by their original order in a program. In doing so, the processor can avoid being idle while waiting for the preceding instruction to complete and can, in the meantime, process the next instructions that are able to run immediately and independently.
Dynamic program analysisDynamic program analysis is analysis of computer software that involves executing the program in question (as opposed to static program analysis, which does not). Dynamic program analysis includes familiar techniques from software engineering such as unit testing, debugging, and measuring code coverage, but also includes lesser-known techniques like program slicing and invariant inference. Dynamic program analysis is widely applied in security in the form of runtime memory error detection, fuzzing, dynamic symbolic execution, and taint tracking.
