Visualizing the similarity and pedigree of NEURON ion channel models available on ModelDB
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This paper provides new results on computing simultaneous sparse approximations of multichannel signals over redundant dictionaries using two greedy algorithms. The first one, p-thresholding, selects the S atoms that have the largest p-correlation while ...
The functional anal. of single ion channel proteins presents a serious bottleneck in the process of finding new pharmacol. active compds. Currently available single channel recording methods are not suited for automation and miniaturization. However, new t ...
A method is presented to form gold-electrode-tethered lipid bilayers with exceptionally high elec. resistances. Elec. impedance spectroscopy is used to monitor the bilayer incorporation of a ligand-gated ion channel protein and the modulation of its channe ...
Burnashev in 1976 gave an exact expression for the reliability function of a discrete memoryless channel (DMC) with noiseless feedback. A coding scheme that achieves this exponent needs, in general, to know the statistics of the channel. Suppose now that t ...
The computational power of the neocortex arises from interactions of multiple neurons, which display a wide range of electrical properties. The gene expression profiles underlying this phenotypic diversity are unknown. To explore this relationship, we comb ...
The authors probed the function of receptor protein OmpF by in situ measurement of both the binding of ligands by surface plasmon resonance (SPR) and subsequent changes of the channel activity by impedance spectroscopy (IS). [on SciFinder (R)] ...
Tumor necrosis factor TNF can trigger increases in membrane conductance of mammalian cells in a receptor-independent manner via its lectin-like domain. A lectin-deficient TNF mutant, lacking this activity, was able to bind to artificial liposomes in a pH-d ...
The invention relates to various embodiments of a bioanal. reagent with at least one vesicle, generated from a living cell, and at least one receptor for study of signal transduction. The invention further relates to methods for prodn. of said bioanal. rea ...
(Ecole Polytechnique Federale de Lausanne, Switz.; Zeptosens A.-G.).2002
The coat protein of bacteriophage Pf3 forms discrete and stable ion channels of uniform size in planar bilayers of asolectin. Its primary sequence suggests a channel formed by a bundle of transmembrane helixes. Since the apparent transmembrane region only ...
A regulatory volume decrease is accomplished by parallel activation of Ca(2+)-dependent K+ channels and Ca(2+)-independent Cl- channels in cultured human intestinal epithelial cells (Intestine 407). The anion selectivity of whole-cell currents recorded in ...