Neurorehabilitation and neuroprosthetic technologies to regain motor function following spinal cord injury
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For a complete adult spinal rat to regain some weight-bearing stepping capability, it appears that a sequence of specific proprioceptive inputs that are similar, but not identical, from step to step must be generated over repetitive step cycles. Furthermor ...
Locomotor training on treadmills can improve recovery of stepping in spinal cord injured animals and patients. Likewise, lesioned rats treated with antibodies against the myelin associated neurite growth inhibitory protein, Nogo-A, showed increased regener ...
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We investigated the role of afferent information during recovery of coordinated rhythmic activity of the hindlimbs in rats with a complete spinal cord section (approximately T8) and unilateral deafferentation (T12-S2) to answer the following questions: (1) ...
We are interested in developing and building an experimental system for controlling a quadruped robot with a brain-derived signal of a rat. We recorded large ensembles of neurones in left M1 and right M1 and S1 using chronically implanted multi-electrodes ...
BACKGROUND: In the field of neuroscience microarray gene expression profiles on anatomically defined brain structures are being used increasingly to study both normal brain functions as well as pathological states. Fluorescent tracing techniques in brain t ...
Spinal cord injuries (SCIs) in humans and experimental animals are often associated with varying degrees of spontaneous functional recovery during the first months after injury. Such recovery is widely attributed to axons spared from injury that descend fr ...
Locomotor training improves function after a spinal cord injury both in experimental and clinical settings. The activity-dependent mechanisms underlying such improvement, however, are sparsely understood. Adult rats received a complete spinal cord transect ...
We hypothesized that epidural spinal cord stimulation (ES) and quipazine (a serotonergic agonist) modulates the excitability of flexor and extensor related intraspinal neural networks in qualitatively unique, but complementary, ways to facilitate locomotio ...
Each year, following an accident or illness, over 200 new cases of paraplegia occur in Switzerland, and 1000 in France. This makes 7’000, respectively 40'000 para- etraplegic patients in these countries. Since the Second World War, methods available for th ...
Sashi S Kommu, Published by I-Tech Education and Publishing2007
