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Exploring new therapeutic strategies for Huntington's Disease

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Exploring new therapeutic strategies for Huntington's Disease

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N-terminal mutant huntingtin deposition correlates with CAG repeat length and symptom onset, but not neuronal loss in Huntington's disease

Humoral Responses Against Variants of Concern by COVID-19 mRNA Vaccines in Immunocompromised Patients

Targeting molecular surfaces to engineer novel protein-based immunogens and inhibitors

A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response

A high-throughput cell- and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma

Rationally designed Human Cytomegalovirus gB nanoparticle vaccine with improved immunogenicity

Ultrasensitive quantitative measurement of huntingtin phosphorylation at residue S13

The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain

Development of novel methods and tools to decipher the huntingtin post-translation modifications code

Expanding beyond the natural protein repertoire to engineer targeted vaccines and diagnostics