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Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity

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Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity

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Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1(T315I) and BCR-ABL1(T315I-E255K)

Allosteric regulation and targeting of Bruton's tyrosine kinase (Btk) in B-cell lymphoma

Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- and lipid-binding properties of Tau

Rapid Screen for Tyrosine Kinase Inhibitor Resistance Mutations and Substrate Specificity

γ-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia

Cytosolic delivery and characterization of monobodies interfering with SH2 domain-phosphotyrosine interactions

Allosteric kinase inhibitors

Differential signaling networks of Bcr-Abl p210 and p190 kinases in leukemia cells defined by functional proteomics

Physiological regulation of the CDK16/PCTAIRE-1 protein kinase and its proposed role in the brain