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The application of microfluidics in the field of surface-based assays and more specifically, the spatial molecular profiling of tumor tissues has gained a lot of interest, especially with the increased interest in personalized medicine and targeted therapy ...
Binary fluids are present in a wide variety of systems at microscales, such as microfluidic devices containing drops, fluids with air bubbles trapped in them, and devices designed to mix fluids or to make two fluid substances react. Microfluidics devices a ...
Liquid-liquid microfluidic systems rely on the intricate control over the fluid properties of either miscible or immiscible mixtures. Herein, we report on the use of partially miscible binary liquid mixtures that lend their microfluidic properties from a h ...
A Suspended microchannel resonator (SMR) is composed by a hollow resonant structure containing embedded microfluidic channel. This device allows to circumvent the viscous damping confining the fluid to the inside of the resonant beam. The goal of this proj ...
Capsules are often employed to prolong the shelf-life of active ingredients such as many drugs, food additives, or cosmetic substances because they delay their oxidation or prevent interactions with molecules contained in the surrounding. If designed prope ...
Double emulsions are often used as containers to perform high throughput screening assays and as templates for capsules. These applications require double emulsions to be mechanically stable such that they do not coalesce during processing and storage. A p ...
A fluid droplet suspended in an extensional flow of moderate intensity may break into pieces, depending on the amplitude of the initial droplet deformation. In subcritical uniaxial extensional flow the nonbreaking base state is linearly stable, implying th ...
Drops are often used as picoliter-sized reaction vessels, for example for high-throughput screening assays, or as templates to produce particles of controlled sizes and compositions. Many of these applications require close control over the size of drops, ...
This PhD thesis aims at developing a system which can measure the mechanical properties of fluidic samples in the picoliter range. The ultimate goal is the characterization of cancer cells and viscoelastic fluids (i.e. biological fluids), in order to study ...
A non-intrusive method is presented for measuring different fluidic properties in a microfluidic chip by optically monitoring the flow of droplets. A neural network is used to extract the desired information from the images of the droplets. We demonstrate ...