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Biodegradable HEMA-based hydrogels with enhanced mechanical properties

Related publications (32)

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Hydrogels are among the first materials expressly designed for their use in biomedicine. However, state-of-the-art applications of hydrogels are severely limited because they are typically either too soft or too brittle such that they cannot bear significa ...
EPFL2023

Supramolecular Modifications of Semicrystalline Polymers

Michael Alan Giffin

Supramolecular interactions play an important role in defining the structure and the resulting mechanical properties of materials. For instance, interchain hydrogen-bonding in PAs gives them superior strength and stiffness in engineering materials, while t ...
EPFL2023

Rheological Properties of Ionically Crosslinked Viscoelastic 2D Films vs. Corresponding 3D Bulk Hydrogels

Esther Amstad, Gaia De Angelis

Ionically crosslinked hydrogels containing metal coordination motifs have piqued the interest of researchers in recent decades due to their self-healing and adhesive properties. In particular, catechol-functionalized bulk hydrogels have received a lot of a ...
AMER CHEMICAL SOC2023

Mechanical Reinforcement of Hydrogels through Physical Crosslinks and Double Network Granular Architecture

Alvaro Lino Boris Charlet

Throughout nature, organisms fabricate a myriad of materials to sustain their lifestyle. Many of the soft materials are composed of water-swollen networks of organic molecules, so-called hydrogels. They generally contribute to the mechanical integrity of t ...
EPFL2022

Biocompatible Chitosan-Based Hydrogels for Bioabsorbable Wound Dressings

Maria-Alexandra Paun

Supramolecular hydrogels based on chitosan and monoaldehydes are biomaterials with high potential for a multitude of bioapplications. This is due to the proper choice of the monoaldehyde that can tune the hydrogel properties for specific practices. In this ...
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All-polymeric transient neural probe for prolonged in-vivo electrophysiological recordings

Diego Ghezzi, Laura Ferlauto, Paola Vagni, Adele Fanelli, Elodie Geneviève Zollinger

Transient bioelectronics has grown fast, opening possibilities never thought before. In medicine, transient implantable devices are interesting because they could eliminate the risks related to surgical retrieval and reduce the chronic foreign body reactio ...
2021

Microstructured biodegradable fibers for advanced controlled release

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Biodegradable polymers are increasingly at the heart of therapeutic devices. Particularly in the form of thin and elongated fibers, they offer an effective strategy for controlled-release in a variety of biomedical configurations such as sutures, scaffolds ...
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Multifunctional hybrid alginate-based hydrogels for cell immobilization

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Cell therapy could be a solution for many diseases that currently pose a huge health burden on patients. Especially, cell therapies based on cell microencapsulation are of great interest. Immunoprotection of cells would allow to avoid the need for immunosu ...
EPFL2020

Released Diclofenac Sodium Salt From Chitosan Embedding In A Hydrogel Matrix. A Theoretical And Experimental Study

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Two formulations embedding diclofenac sodium salt into a chitosan hydrogel matrix with different crosslinking degree were prepared by in situ hydrogelation. The formulations were investigated by polarized light microscopy and scanning electron microscopy, ...
UNIV POLITEHNICA BUCHAREST, SCI BULL2020

5-Fluorouracil Release from Chitosan-Based Matrix. Experimental and Theoretical Aspects

Maria-Alexandra Paun

A series of four drug release formulations based on 5-fluorouracil encapsulated into a chitosan-based matrix were prepared by in situ hydrogelation with 3,7-dimethyl-2,6-octadienal. The formulations were investigated from structural and morphological aspec ...
2020

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