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Timber Folded Plate Structures – Folded Form Analysis

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Switch-peptides: controlling biological function and self-assembly of amyloid ß-derived peptides using enzyme-triggered acyl migrations

Sonia Dos Santos

Conformational transitions of peptides and proteins have recently moved to the center of interest in various domains of research at the interface of chemistry, biology, and medicine due to their implication in an increasing number of diseases in which the ...

EPFL2005

The central region of the matrix protein p17 of HIV-1 is known to be essential during virus assembly. We substituted alanines for amino acid triplets in this region of p17 (amino acid residues 47 to 55: NPG LLE TSE). Introduction of the respective mutation ...

Walter de Gruyter2004

Molecular dynamics simulations of structural changes during procaspase 3 activation

Ursula Röthlisberger

Mol. dynamics simulations (MDS) of the structural rearrangements on the pathway leading to procaspase 3 (I) activation are presented. A retrostructural approach was used to build I from mature caspase 3 (II). The peptide bond that was cleaved during enzyme ...

2004

A tensegrity is a lightweight space reticulated structure consisting of compression members — struts — surrounded by a network of tension members — cables — that provide rigidity and stability. They can be easily dismantled and therefore, they provide inno ...

EPFL2003

Transposing multimedia into a virtual course

Olivier Burdet

The present paper describes the challenges posed by transposing a successful conventional course into an – hopefully – equally successful web-based course, with the name i-Structures. This work is under way as part of the Swiss Virtual Campus project. The ...

4th International Conference on New Educational Environments2002

A review is given with 62 refs. on the art of template-based protein de novo design, with special emphasis on progress in peptide synthesis and template design and show that some fundamental questions in protein assembly, structure and function can be appr ...

1997

The influence of random microstructures and strengths on mechanical performance of advanced ceramics is now being recognized as critical. Experimental results on new ceramics demonstrate the importance of stochastic phenomena, particularly in fiber-reinfor ...

1996