Conjugates of photosensitizers and oligonucleotides for selective photochemiotherapy
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Photodynamic therapy (PDT) for cancer in the esophagus and bronchi with red (630 nm) light may occasionally lead to wall perforation and fistula. Therefore, the clin. use of a less penetrating wavelength (514 nm) was investigated for the curative treatment ...
BACKGROUND AND OBJECTIVE: Under standardized conditions (drug and light dose, timing), the result of the photodynamic therapy (PDT) of carcinomas of the esophagus with tetra(meta-hydroxyphenyl)chlorin (mTHPC) shows large variations between patients. STUDY ...
The electrochem. oxidn. of phenol in the presence of NaCl for wastewater treatment was studied at Ti/SnO2 and Ti/IrO2 anodes. The presence of NaCl catalyzes the anodic oxidn. of phenol only at Ti/IrO2 anodes due to the participation of electrogenerated ClO ...
(E)-RCH:CH(CH2)nOH (n = 2,3,5,7; R = Et, pentyl, hexyl, E-CH:CHMe) were obtained in 69-78% yield in a 1-pot reaction by treating HO(CH2)nCH2P+Ph3 Br- with PhLi in tetrahydrofuran-EtiO, followed by addn. of RCHO, treatment with HCl-Et2O, and with KOCMe3. [o ...
The conventional treatment for the cure of esophageal cancer is surgical resection. Esophageal cancer, when detected at an early stage, has a very good probability of being eradicated by less aggressive procedures, and photodynamic therapy has proven to be ...
Cancer, when detected at an early stage, has a very good probability of being eradicated by surgery or radiotherapy. However, less aggressive treatments also tend to provide high rates of cure without the side effects of radical therapy. We report on the r ...
The aim was to examine the anodic oxidn. of some benzene derivs. (model org. pollutants) at Pt and DSA (dimensionally stable anodes) type anodes to elucidate the possibilities of the electrochem. method and to elucidate the mechanism of the reaction. ...