Publication
Fibrinogen fusion proteins, methods of making, and methods of using fibrinogen fusion proteins are described. In a preferred embodiment the fibrinogen fusion protein contains a truncated Aa chain of fibrinogen. The Aa chain contains truncation site, which is a deletion of amino acids at its C-terminal region. A non-fibrinogen protein or peptide is C-terminally attached to the truncation site. The fibrinogen fusion proteins can be used alone or mixed with native fibrinogen to form fibrin polymer.
Paul Joseph Dyson, Ning Yan, Yefeng Wang, Shunlin Zhang, Yu Han
Jérôme Waser, Eliott Hugo Joran Le Du, Marion Marie-Agnès Garreau