Sanger sequencingSanger sequencing is a method of DNA sequencing that involves electrophoresis and is based on the random incorporation of chain-terminating dideoxynucleotides by DNA polymerase during in vitro DNA replication. After first being developed by Frederick Sanger and colleagues in 1977, it became the most widely used sequencing method for approximately 40 years. It was first commercialized by Applied Biosystems in 1986. More recently, higher volume Sanger sequencing has been replaced by next generation sequencing methods, especially for large-scale, automated genome analyses.
Environmental conflictEnvironmental conflicts or ecological distribution conflicts (EDCs) are social conflicts caused by environmental degradation or by unequal distribution of environmental resources. The Environmental Justice Atlas documented 3,100 environmental conflicts worldwide as of April 2020 and emphasised that many more conflicts remained undocumented. Parties involved in these conflicts include locally affected communities, states, companies and investors, and social or environmental movements; typically environmental defenders are protecting their homelands from resource extraction or hazardous waste disposal.
Environmental justiceEnvironmental justice or eco-justice, is a social movement to address environmental injustice, which occurs when poor and marginalized communities are harmed by hazardous waste, resource extraction, and other land uses from which they do not benefit. The movement has generated hundreds of studies showing that exposure to environmental harm is inequitably distributed. The movement began in the United States in the 1980s. It was heavily influenced by the American civil rights movement and focused on environmental racism within rich countries.
Terrain cartographyTerrain cartography or relief mapping is the depiction of the shape of the surface of the Earth on a map, using one or more of several techniques that have been developed. Terrain or relief is an essential aspect of physical geography, and as such its portrayal presents a central problem in cartographic design, and more recently geographic information systems and geovisualization. The most ancient form of relief depiction in cartography, hill profiles are simply illustrations of mountains and hills in profile, placed as appropriate on generally small-scale (broad area of coverage) maps.
Third-generation sequencingThird-generation sequencing (also known as long-read sequencing) is a class of DNA sequencing methods currently under active development. Third generation sequencing technologies have the capability to produce substantially longer reads than second generation sequencing, also known as next-generation sequencing. Such an advantage has critical implications for both genome science and the study of biology in general. However, third generation sequencing data have much higher error rates than previous technologies, which can complicate downstream genome assembly and analysis of the resulting data.
Human genomeThe human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. These are usually treated separately as the nuclear genome and the mitochondrial genome. Human genomes include both protein-coding DNA sequences and various types of DNA that does not encode proteins. The latter is a diverse category that includes DNA coding for non-translated RNA, such as that for ribosomal RNA, transfer RNA, ribozymes, small nuclear RNAs, and several types of regulatory RNAs.
Scale (geography)In geography, scale is the level at which a geographical phenomenon occurs or is described. This concept is derived from the map scale in cartography. Geographers describe geographical phenomena and differences using different scales. From an epistemological perspective, scale is used to describe how detailed an observation is, while ontologically, scale is inherent in the complex interaction between society and nature. The concept of scale is central to geography.
Arbia's law of geographyArbia’s law of geography states, "Everything is related to everything else, but things observed at a coarse spatial resolution are more related than things observed at a finer resolution." Originally proposed as the 2nd law of geography, this is one of several laws competing for that title. Because of this, Arbia's law is sometimes referred to as the second law of geography, or Arbia's second law of geography.
Environmental racismEnvironmental racism, ecological racism or ecological apartheid is a form of institutional racism leading to landfills, incinerators, and hazardous waste disposal being disproportionately placed in communities of color. Internationally, it is also associated with extractivism, which places the environmental burdens of mining, oil extraction, and industrial agriculture upon indigenous peoples and poorer nations largely inhabited by people of color.
GeomorphometryGeomorphometry, or geomorphometrics (gê + morphḗ + métron), is the science and practice of measuring the characteristics of terrain, the shape of the surface of the Earth, and the effects of this surface form on human and natural geography. It gathers various mathematical, statistical and image processing techniques that can be used to quantify morphological, hydrological, ecological and other aspects of a land surface. Common synonyms for geomorphometry are geomorphological analysis (after geomorphology), terrain morphometry, terrain analysis, and land surface analysis.