Nanosensors for early cancer detection and for therapeutic drug monitoring
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The paper proposes a learning approach to support medical researchers in the context of in-vivo cancer imaging, and specifically in the analysis of Dynamic Contrast-Enhanced MRI (DCE-MRI) data. Tumour heterogeneity is characterized by identifying regions w ...
The present invention relates to a method and a kit for predicting the efficacy of cancer therapy in a subject who has undergone or is undergoing chemotherapy treatment for cancer. ...
New results are presented on the pharmacokinetics of the fluorescing fraction of Photofrin II in patients with an early cancer in the oesophagus or the buccal cavity. The light-induced fluorescence signal shows a relatively high contrast between tumor and ...
Cancer: growth caused by uncontrolled and abnormal cell division, resulting in a non-structured mass or tumor, serving no beneficial purpose to the body. Even though cancer is one of the leading fatal diseases of today's world, with no distinction for age, ...
We have at our disposal observations relating to the mortality due to different types of cancer and we wish to compare them with a theoretical model. The usual models lead to increased mortality with increasing age, instead of the drop which is observed af ...
Meta(tetrahydroxyphenyl)chlorin (m-THPC) is a new photosensitizer currently undergoing clin. trials at Lausanne's CHUV hospital for photodynamic therapy (PDT) of early cancer in the upper aerodigestive tract. The illumination of m-THPC with light at 650 nm ...
In Part 1 of this article we developed an approach for the calculation of cancer effect measures for life cycle assessment (LCA). In this article, we propose and evaluate the method for the screening of noncancer toxicological health effects. This approach ...
The combined and ordered sequential action of glycosidases and glycosyltransferases in mammalian cell compartments leads to the addition of defined glycans to proteins and lipids. Altered glycosylation patterns, neoexpression, underexpression or overexpres ...
Head and neck (H&N) cancer patients have a high incidence of second primary tumors in the tracheobronchial tree. Diagnostic autofluorescence endoscopy (DAFE) has shown promising results in the detection of early neoplastic and pre-neoplastic changes in the ...
A rare EcoRI restriction fragment length polymorphism (RFLP) in the 3' end of the human c-mos locus has been identified in DNA from patients with breast tumors, esophageal carcinomas and leukemias. Until now, this RFLP has not been found in normal populati ...