High-content screeningHigh-content screening (HCS), also known as high-content analysis (HCA) or cellomics, is a method that is used in biological research and drug discovery to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell in a desired manner. Hence high content screening is a type of phenotypic screen conducted in cells involving the analysis of whole cells or components of cells with simultaneous readout of several parameters.
Guttman scaleIn the analysis of multivariate observations designed to assess subjects with respect to an attribute, a Guttman scale (named after Louis Guttman) is a single (unidimensional) ordinal scale for the assessment of the attribute, from which the original observations may be reproduced. The discovery of a Guttman scale in data depends on their multivariate distribution's conforming to a particular structure (see below).
Avatar (2009 film)Avatar (marketed as James Cameron's Avatar) is a 2009 epic science fiction film directed, written, co-produced, and co-edited by James Cameron and starring Sam Worthington, Zoe Saldana, Stephen Lang, Michelle Rodriguez, and Sigourney Weaver. It is the first installment in the Avatar film series. It is set in the mid-22nd century, when humans are colonizing Pandora, a lush habitable moon of a gas giant in the Alpha Centauri star system, in order to mine the valuable mineral unobtanium.
