Antimicrobial peptidesAntimicrobial peptides (AMPs), also called host defence peptides (HDPs) are part of the innate immune response found among all classes of life. Fundamental differences exist between prokaryotic and eukaryotic cells that may represent targets for antimicrobial peptides. These peptides are potent, broad spectrum antimicrobials which demonstrate potential as novel therapeutic agents. Antimicrobial peptides have been demonstrated to kill Gram negative and Gram positive bacteria, enveloped viruses, fungi and even transformed or cancerous cells.
Molecular machineMolecular machines are a class of molecules typically described as an assembly of a discrete number of molecular components intended to produce mechanical movements in response to specific stimuli, mimicking macromolecular devices such as switches and motors. Naturally occurring or biological molecular machines are responsible for vital living processes such as DNA replication and ATP synthesis. Kinesins and ribosomes are examples of molecular machines, and they often take the form of multi-protein complexes.
Muscle contractionMuscle contraction is the activation of tension-generating sites within muscle cells. In physiology, muscle contraction does not necessarily mean muscle shortening because muscle tension can be produced without changes in muscle length, such as when holding something heavy in the same position. The termination of muscle contraction is followed by muscle relaxation, which is a return of the muscle fibers to their low tension-generating state.
Leaf springA leaf spring is a simple form of spring commonly used for suspension in wheeled vehicles. Originally called a laminated or carriage spring, and sometimes referred to as a semi-elliptical spring, elliptical spring, or cart spring, it is one of the oldest forms of vehicle suspension. A leaf spring is one or more narrow, arc-shaped, thin plates that are attached to the axle and chassis in a way that allows the leaf spring to flex vertically in response to irregularities in the road surface.
Spring (device)A spring is a device consisting of an elastic but largely rigid material (typically metal) bent or molded into a form (especially a coil) that can return into shape after being compressed or extended. Springs can store energy when compressed. In everyday use the term often refers to coil springs, but there are many different spring designs. Modern springs are typically manufactured from spring steel. An example of a non-metallic spring is the bow, made traditionally of flexible yew wood, which when drawn stores energy to propel an arrow.
Coronavirus spike proteinSpike (S) glycoprotein (sometimes also called spike protein, formerly known as E2) is the largest of the four major structural proteins found in coronaviruses. The spike protein assembles into trimers that form large structures, called spikes or peplomers, that project from the surface of the virion. The distinctive appearance of these spikes when visualized using negative stain transmission electron microscopy, "recalling the solar corona", gives the virus family its main name.
Complex numberIn mathematics, a complex number is an element of a number system that extends the real numbers with a specific element denoted i, called the imaginary unit and satisfying the equation ; every complex number can be expressed in the form , where a and b are real numbers. Because no real number satisfies the above equation, i was called an imaginary number by René Descartes. For the complex number , a is called the , and b is called the . The set of complex numbers is denoted by either of the symbols or C.
MainspringA mainspring is a spiral torsion spring of metal ribbon—commonly spring steel—used as a power source in mechanical watches, some clocks, and other clockwork mechanisms. Winding the timepiece, by turning a knob or key, stores energy in the mainspring by twisting the spiral tighter. The force of the mainspring then turns the clock's wheels as it unwinds, until the next winding is needed. The adjectives wind-up and spring-powered refer to mechanisms powered by mainsprings, which also include kitchen timers, metronomes, music boxes, wind-up toys and clockwork radios.
Calcium signalingCalcium signaling is the use of calcium ions (Ca2+) to communicate and drive intracellular processes often as a step in signal transduction. Ca2+ is important for cellular signalling, for once it enters the cytosol of the cytoplasm it exerts allosteric regulatory effects on many enzymes and proteins. Ca2+ can act in signal transduction resulting from activation of ion channels or as a second messenger caused by indirect signal transduction pathways such as G protein-coupled receptors.
Complex logarithmIn mathematics, a complex logarithm is a generalization of the natural logarithm to nonzero complex numbers. The term refers to one of the following, which are strongly related: A complex logarithm of a nonzero complex number , defined to be any complex number for which . Such a number is denoted by . If is given in polar form as , where and are real numbers with , then is one logarithm of , and all the complex logarithms of are exactly the numbers of the form for integers .