Tumour heterogeneityTumour heterogeneity describes the observation that different tumour cells can show distinct morphological and phenotypic profiles, including cellular morphology, gene expression, metabolism, motility, proliferation, and metastatic potential. This phenomenon occurs both between tumours (inter-tumour heterogeneity) and within tumours (intra-tumour heterogeneity). A minimal level of intra-tumour heterogeneity is a simple consequence of the imperfection of DNA replication: whenever a cell (normal or cancerous) divides, a few mutations are acquired—leading to a diverse population of cancer cells.
Bone tumorA bone tumor is an abnormal growth of tissue in bone, traditionally classified as noncancerous (benign) or cancerous (malignant). Cancerous bone tumors usually originate from a cancer in another part of the body such as from lung, breast, thyroid, kidney and prostate. There may be a lump, pain, or neurological signs from pressure. A bone tumor might present with a pathologic fracture. Other symptoms may include fatigue, fever, weight loss, anemia and nausea. Sometimes there are no symptoms and the tumour is found when investigating another problem.
Mac OS X ServerMac OS X Server is a discontinued series of Unix-like server operating systems developed by Apple Inc. based on macOS. It provided server functionality and system administration tools, and tools to manage both macOS-based computers and iOS-based devices, network services such as a mail transfer agent, AFP and SMB servers, an LDAP server, and a domain name server, as well as server applications including a Web server, database, and calendar server.
Positron emission tomographyPositron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption. Different tracers are used for various imaging purposes, depending on the target process within the body. For example, -FDG is commonly used to detect cancer, NaF is widely used for detecting bone formation, and oxygen-15 is sometimes used to measure blood flow.
Rhapsody (operating system)Rhapsody is an operating system that was developed by Apple Computer after its purchase of NeXT in the late 1990s. It is the fifth major release of the Mach-based operating system that was developed at NeXT in the late 1980s, previously called OPENSTEP and NEXTSTEP. Rhapsody was targeted to developers for a transition period between the Classic Mac OS and Mac OS X. Rhapsody represented a new and exploratory strategy for Apple, more than an operating system, and runs on x86-based PCs and on Power Macintosh.
Brain tumorA brain tumor occurs when abnormal cells form within the brain. There are two main types of tumors: malignant tumors and benign (non-cancerous) tumors. These can be further classified as primary tumors, which start within the brain, and secondary tumors, which most commonly have spread from tumors located outside the brain, known as brain metastasis tumors. All types of brain tumors may produce symptoms that vary depending on the size of the tumor and the part of the brain that is involved.
WatchOSwatchOS is the operating system of the Apple Watch, developed by Apple Inc. It is based on iOS, the operating system used by the iPhone, and has many similar features. It was released on April 24, 2015, along with the Apple Watch, the only device that runs watchOS. watchOS exposes an API called WatchKit for developer use. The second version, watchOS 2, included support for native third-party apps and other improvements, and was released on September 21, 2015.
MacOSmacOS (ˌmækoʊˈɛs; previously OS X and originally Mac OS X) is an operating system developed and marketed by Apple Inc. since 2001. It is the primary operating system for Apple's Mac computers. Within the market of desktop and laptop computers, it is the second most widely used desktop OS, after Microsoft Windows and ahead of Linux (including ChromeOS). macOS succeeded the classic Mac OS, a Mac operating system with nine releases from 1984 to 1999.
Lymph nodeA lymph node, or lymph gland, is a kidney-shaped organ of the lymphatic system and the adaptive immune system. A large number of lymph nodes are linked throughout the body by the lymphatic vessels. They are major sites of lymphocytes that include B and T cells. Lymph nodes are important for the proper functioning of the immune system, acting as filters for foreign particles including cancer cells, but have no detoxification function. In the lymphatic system a lymph node is a secondary lymphoid organ.
Cervical lymph nodesCervical lymph nodes are lymph nodes found in the neck. Of the 800 lymph nodes in the human body, 300 are in the neck. Cervical lymph nodes are subject to a number of different pathological conditions including tumours, infection and inflammation. There are approximately 300 lymph nodes in the neck, and they can be classified in a number of different ways.