Physical cosmologyPhysical cosmology is a branch of cosmology concerned with the study of cosmological models. A cosmological model, or simply cosmology, provides a description of the largest-scale structures and dynamics of the universe and allows study of fundamental questions about its origin, structure, evolution, and ultimate fate. Cosmology as a science originated with the Copernican principle, which implies that celestial bodies obey identical physical laws to those on Earth, and Newtonian mechanics, which first allowed those physical laws to be understood.
Gene knockoutGene knockouts (also known as gene deletion or gene inactivation) are a widely used genetic engineering technique that involves the targeted removal or inactivation of a specific gene within an organism's genome. This can be done through a variety of methods, including homologous recombination, CRISPR-Cas9, and TALENs. One of the main advantages of gene knockouts is that they allow researchers to study the function of a specific gene in vivo, and to understand the role of the gene in normal development and physiology as well as in the pathology of diseases.
Delayed onset muscle sorenessDelayed onset muscle soreness (DOMS) is the pain and stiffness felt in muscles after unaccustomed or strenuous exercise. The soreness is felt most strongly 24 to 72 hours after the exercise. It is thought to be caused by eccentric (lengthening) exercise, which causes small-scale damage (microtrauma) to the muscle fibers. After such exercise, the muscle adapts rapidly to prevent muscle damage, and thereby soreness, if the exercise is repeated. Delayed onset muscle soreness is one symptom of exercise-induced muscle damage.
HomeosisIn evolutionary developmental biology, homeosis is the transformation of one organ into another, arising from mutation in or misexpression of certain developmentally critical genes, specifically homeotic genes. In animals, these developmental genes specifically control the development of organs on their anteroposterior axis. In plants, however, the developmental genes affected by homeosis may control anything from the development of a stamen or petals to the development of chlorophyll.
Astronomical clockAn astronomical clock, horologium, or orloj is a clock with special mechanisms and dials to display astronomical information, such as the relative positions of the Sun, Moon, zodiacal constellations, and sometimes major planets. The term is loosely used to refer to any clock that shows, in addition to the time of day, astronomical information. This could include the location of the Sun and Moon in the sky, the age and Lunar phases, the position of the Sun on the ecliptic and the current zodiac sign, the sidereal time, and other astronomical data such as the Moon's nodes for indicating eclipses), or a rotating star map.
Speaking clockA speaking clock or talking clock is a live or recorded human voice service, usually accessed by telephone, that gives the correct time. The first telephone speaking clock service was introduced in France, in association with the Paris Observatory, on 14 February 1933. The format of the service is similar to that of radio time signal services. At set intervals (e.g. ten seconds) a voice announces (for example) "At the third stroke, the time will be twelve forty-six and ten seconds......", with three beeps following.
Spontaneous orderSpontaneous order, also named self-organization in the hard sciences, is the spontaneous emergence of order out of seeming chaos. The term "self-organization" is more often used for physical changes and biological processes, while "spontaneous order" is typically used to describe the emergence of various kinds of social orders in human social networks from the behavior of a combination of self-interested individuals who are not intentionally trying to create order through planning.