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Development of an effective cell seeding technique: simulation, implementation and analysis of contributing factors

Related publications (35)

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Microtechnologies to Map the Fate of Single Stem Cells and their Progeny

Stefan Kobel

Since stem cells have the unique ability to produce more of themselves (i.e. to "self-renew") and to generate specialized tissue cells, they are an ideal source of cells for regenerative medicine and in vitro tissue models. In order to fully exploit this p ...

EPFL2012

Micro-engineering the Cerebral Cortical Cell Niche

Anja Kunze

A major problem in traditional cell culture methods, such as Petri dishes and culture flasks, is the very simplified artificial environment around the cells. Traditional cell culture methods lack features of the native cell niche, such as gradients and cel ...

EPFL2012

Microdrop Printing of Hydrogel Bioinks into 3D Tissue-Like Geometries

Jürgen Brugger, Philippe Renaud, Matthias Lütolf, Thomas Michael Braschler, Kristopher Pataky, Andrea Negro

An optimized 3D inkjet printing process is demonstrated for structuring alginate into a tissue-like microvasculature capable of supporting physiological flow rates. Optimizing the reaction at the single-droplet level enables wet hydrogel droplets to be sta ...

Wiley-Blackwell2012

Realistic Modeling of 3D Plasmonic Systems

Andreas Kern

Interest in plasmonic nanostructures has recently multiplied due to their extraordinary optical properties. When resonantly excited, these tiny metallic systems exhibit a strong and localized optical field enhancement. Applications exploiting this effect e ...

EPFL2011

Scientific Computing For Aluminum Production

Jacques Rappaz, Marco Picasso, Gilles Steiner, Thomas Hofer

Numerical simulation in aluminum production envolves many different topics, this paper is dedicated to some aspects of two of them. In the first part, a numerical approach for the computation of the motion of the fluids in an electrolitic cell is presented ...

2009

Studies on scaffold design for tissue engineering applications

The aim of tissue engineering is to regenerate tissue for the purpose of repairing or replacing diseased or injured tissue. Therefore, cells that are able to proliferate are seeded on scaffolds that provide mechanical stability and direct the three-dimensi ...

EPFL2009

Part load flow in radial centrifugal pumps

Olivier Braun

Centrifugal pumps are required to sustain a stable operation of the system they support under all operating conditions. Minor modifications of the surfaces defining the pump's water passage can influence the tendency to unstable system operation significan ...

EPFL2009

Modelling and numerical simulation for yacht design

Alfio Quarteroni, Nicola Parolini

In the past few years, Computational Fluid Dynamics (CFD) has become an essential tool in the design and optimization of racing sailboats and in particular America's Cup yachts. The prevalent role of CFD in the design process is demonstrated by the number ...

Strategic Analysis Inc.2007

Modélisation mathématique et simulation numérique des phénomènes dynamiques et thermiques apparaissant dans un glacier

Pierre Kirner

In this work, two problems linked to glacier modeling are investigated. We propose an optimisation method for studying the flow of the ice and we present a numerical study about glacier thermal phenomena. In the first chapter of this thesis, we expose the ...

EPFL2007

Effect of solute dissolution kinetics on cloud droplet formation: Extended Köhler theory

Athanasios Nenes

This study focuses on the importance of solute dissolution kinetics for cloud droplet formation. To comprehensively account for the kinetics, a numerical model of the process was developed. Simulations of cloud droplet growth were performed for solute diff ...

Blackwell Publishing Ltd2007