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Label-Free Quantification Proteomics for the Identification of Mesenchymal Stromal Cell Matrisome Inside 3D Poly(Ethylene Glycol) Hydrogels
Related publications (42)
Oral transfer of chemical cues, growth proteins and hormones in social insects
Laure Menin, Oksana Riba Grognuz, Laurent Keller
Social insects frequently engage in oral fluid exchange trophallaxis between adults, and between adults and larvae. Although trophallaxis is widely considered a food-sharing mechanism, we hypothesized that endogenous components of this fluid might underlie ...
Elife Sciences Publications Ltd2016On-chip mesoporous functionalized magnetic microspheres for protein sequencing by extended bottom-up mass spectrometry
Hubert Girault, Yury Tsybin, Natalia Gasilova, Liang Qiao, Kristina Srzentic
Limited amount and extreme concentration variability of proteomic-related samples require efficient analyte preconcentration and purification prior to the mass spectrometry (MS)-based analysis. Preferably, these steps should be coupled on-line with chosen ...
American Chemical Society2016Balgacyclamides, Antiplasmodial Heterocyclic Peptides from Microcystis aeruguinosa EAWAG 251
Cyril Portmann, Karl Gademann, Emilie Baudat, Laeticia Da Silva, Simon Sieber
The isolation and structural characterization of three new heterocyclic and macrocyclic peptides, balgacyclamides A C, from Microcystis aeruginosa EAWAG 251 are reported. The constitutions were determined by 2D-NMR methods and mass spectrometry, and the co ...
Amer Chemical Soc2014Standard addition strip for quantitative electrostatic spray ionization mass spectrometry analysis: Determination of caffeine in drinks
Hubert Girault, Christophe Roussel, Liang Qiao, Elena Tobolkina
Standard addition strips were prepared for the quantitative determination of caffeine in different beverages by electrostatic spray ionisation mass spectrometry (ESTASI-MS). The gist of this approach is to dry spots of caffeine solutions with different con ...
Elsevier2014Advances in Structural Elucidation of Small Molecules via High Performance Mass Spectrometry
Qualitative and quantitative analyte analysis is omnipresent: from quality control in food, pharmaceutical, biotechnology industries, to new molecular syntheses, detection of explosives and drugs, as well as natural compound mixture analysis, such as crude ...
EPFL2014Spectroscopic studies of peptide fragments produced by collision-induced dissociation
Tandem mass spectrometry (MS/MS) combined with collision-induced dissociation (CID) is a key method for primary structure determination of peptides and proteins. Collisionally activated peptides undergo statistical dissociation, forming a series of backbon ...
EPFL2014Empirical multi-dimensional space for scoring peptide spectrum matches in shotgun proteomics
Yury Tsybin, Unige Anna Laskay
Data-dependent tandem mass spectrometry (MS/MS) is one of the main techniques for protein identification in shotgun proteomics. In a typical LC MS/MS workflow, peptide product ion mass spectra (MS/MS spectra) are compared with those derived theoretically f ...
Amer Chemical Soc2014Ping-Pong Protons: How Hydrogen Bonding Networks Facilitate Heterolytic Bond Cleavages in Peptide Radical Cations
Yury Tsybin, Matthew Wodrich, Konstantin Zhurov
Electron capture and electron transfer dissociation (ECD/ETD) tandem mass spectrometry (MS/MS) are commonly employed techniques for biomolecular analysis. The ECD/ETD process predominately cleaves N-C-alpha peptide backbone bonds, leading to primary sequen ...
Amer Chemical Soc2014Practical Considerations for Improving the Productivity of Mass Spectrometry-based Proteomics
Yury Tsybin, Anton Kozhinov, Luca Fornelli, Kristina Srzentic, Unige Anna Laskay, Oxana Upir
Mass spectrometry (MS) is currently the most sensitive and selective analytical technique for routine peptide and protein structure analysis. Top-down proteomics is based on tandem mass spectrometry (MS/MS) of intact proteins, where multiply charged precur ...
Schweizerische Chemische Gesellschaft2013On the utility of predictive chromatography to complement mass spectrometry based intact protein identification
Yury Tsybin, Hisham Ben Hamidane
The amino acid sequence determines the individual protein three-dimensional structure and its functioning in an organism. Therefore, "reading" a protein sequence and determining its changes due to mutations or post-translational modifications is one of the ...
Springer-Verlag2012