Publications related to A new class of protein biomarkers based on subcellular distribution: application to a mouse liver cancer model

Studying cancer cells phenotypes integrating omics data in human reduced genome-scale metabolic models.

Vassily Hatzimanikatis, Maria Masid Barcon, Vikash Kumar Pandey

Cancer is a leading cause of death in the world, and the mechanisms underlying this disease are still not completely understood. In the last decades, altered tumour metabolism has been recognized as a hallmark of cancer. This has created a resurgence of in ...

2018

Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease

Johan Auwerx, Kristina Schoonjans, Alessia Perino, Vera Monica Lemos Da Silva, Jun Yong Kim, Dongryeol Ryu, Elena Katsyuba, Hongbo Zhang, Keir Joe Menzies, Matthias Alexander Sokrates Stein, Karim Laurent Gariani, Pooja Jha

Background & Aims: To date, no pharmacological therapy has been approved for non-alcoholic fatty liver disease (NAFLD). The aim of the present study was to evaluate the therapeutic potential of poly ADP-ribose polymerase (PARP) inhibitors in mouse models o ...

Elsevier Science Bv2017

Microencapsulation of hepatocytes and mesenchymal stem cells for therapeutic applications

Sandrine Gerber, Jutta Christine Wandrey, Redouan Mahou

Encapsulated hepatocyte transplantation and encapsulated mesenchymal stem cell transplantation are newly developed potential treatments for acute and chronic liver diseases, respectively. Cells are microencapsulated in biocompatible semi-permeable alginate ...

Springer Science+Business Media2017

Visualization of hepatic arteries with 3D ultrasound during intra-arterial therapies

Anaïs Laure Marie-Thérèse Badoual, François Michaud, Alexandre Bigot

Liver cancer represents the second most common cause of cancer-related mortality worldwide. The prognosis is poor with an overall mortality of 95%. Moreover, most hepatic tumors are unresectable due to their advanced stage at discovery or poor underlying l ...

Spie-Int Soc Optical Engineering2016

Inducing Differentiation of Premalignant Hepatic Cells as a Novel Therapeutic Strategy in Hepatocarcinoma

Benita Wolf

Hepatocellular carcinoma (HCC) represents the second leading cause of cancer-related deaths and is reported to be resistant to chemotherapy caused by tumor-initiating cells. These tumor-initiating cells express stem cell markers. An accumulation of tumor-i ...

American Association for Cancer Research2016

Human Hepatocyte-Derived Induced Pluripotent Stem Cells: MYC Expression, Similarities to Human Germ Cell Tumors, and Safety Issues

Marc Samuel Friedli, Carmen Maria Unzu Ezquerro

Induced pluripotent stem cells (iPSC) are a most promising approach to the development of a hepatocyte transplantable mass sufficient to induce long-term correction of inherited liver metabolic diseases, thus avoiding liver transplantation. Their intrinsic ...

2016

Intraoperative image-guided navigation system: development and applicability in 65 patients undergoing liver surgery

Delphine Ribes Lemay, Matthias Peterhans

Image-guided systems have recently been introduced for their application in liver surgery. We aimed to identify and propose suitable indications for image-guided navigation systems in the domain of open oncologic liver surgery and, more specifically, in th ...

2016

3D Vascular Path Planning of Chemo-Embolizations Using Segmented Hepatic Arteries from MR Angiography

Anaïs Laure Marie-Thérèse Badoual

Transcatheter arterial chemo-embolization (TACE) is a therapeutic procedure to treat primary and metastatic liver cancer. It requires prior delineation of the hepatic arteries on magnetic resonance angiography (MRA) data and identification of the vessels s ...

IEEE2016

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A new class of protein biomarkers based on subcellular distribution: application to a mouse liver cancer model

Studying cancer cells phenotypes integrating omics data in human reduced genome-scale metabolic models.

Hyperpolarized Magnetic Resonance Methods to Investigate Metabolic Pathways in Liver and Immune Cells

Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease

Microencapsulation of hepatocytes and mesenchymal stem cells for therapeutic applications

The therapeutic role of NAD+ modulation in fatty liver disease

Visualization of hepatic arteries with 3D ultrasound during intra-arterial therapies

Inducing Differentiation of Premalignant Hepatic Cells as a Novel Therapeutic Strategy in Hepatocarcinoma

Human Hepatocyte-Derived Induced Pluripotent Stem Cells: MYC Expression, Similarities to Human Germ Cell Tumors, and Safety Issues

Intraoperative image-guided navigation system: development and applicability in 65 patients undergoing liver surgery

3D Vascular Path Planning of Chemo-Embolizations Using Segmented Hepatic Arteries from MR Angiography

Graph Chatbot

Chat with Graph Search

Hyperpolarized Magnetic Resonance Methods to Investigate Metabolic Pathways in Liver and Immune Cells

Studying cancer cells phenotypes integrating omics data in human reduced genome-scale metabolic models.

Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease

The therapeutic role of NAD+ modulation in fatty liver disease

Microencapsulation of hepatocytes and mesenchymal stem cells for therapeutic applications

Visualization of hepatic arteries with 3D ultrasound during intra-arterial therapies

Inducing Differentiation of Premalignant Hepatic Cells as a Novel Therapeutic Strategy in Hepatocarcinoma

Human Hepatocyte-Derived Induced Pluripotent Stem Cells: MYC Expression, Similarities to Human Germ Cell Tumors, and Safety Issues

Intraoperative image-guided navigation system: development and applicability in 65 patients undergoing liver surgery

3D Vascular Path Planning of Chemo-Embolizations Using Segmented Hepatic Arteries from MR Angiography