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Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss

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Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss

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Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools

A ribonucleoprotein transfection strategy for CRISPR/Cas9-mediated gene editing and single cell cloning in rainbow trout cells

Variants in USP48 encoding ubiquitin hydrolase are associated with autosomal dominant non-syndromic hereditary hearing loss

Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein

Computational design of anti-CRISPR proteins with improved inhibition potency

Delivery of CRISPR/Cas9 using AAV-PHP.B in the inner ear leads to allele-specific inactivation of the mutated Tmc1 allele and protects auditory function in Beethoven mice

Effect of Single-Point Mutations on Nitric Oxide Rebinding and the Thermodynamic Stability of Myoglobin

Analysis of Inherited Optic Neuropathies

Gene Editing Preserves Visual Functions in a Mouse Model of Retinal Degeneration

A new approach to Cas9-based genome editing in Aspergillus niger that is precise, efficient and selectable