Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine in vitro
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Cell organization into functional multicellular three-dimensional structures is a long-standing challenge. In particular, engineering of vascularized tissues requires both blood and lymphatic neovascular network formation in a simultaneous and coordinated ...
The mammalian intestine is a prototype of a self-renewing organ. The rapid cellular turnover is supported by proliferating progenitors located in the intestinal crypt, which is also the stem cell location. Homeostasis of the intestinal epithelium has to be ...
Downstream of hydroelectric storage dams, the rivers suffer from rapid, frequent and intense flow variations linked to the power production constraints. Subjected to this hydropeaking phenomenon, the fish population suffers from a known decline. In the res ...
The fish early life-stage (FELS) test guideline (OECD 210 or OCSPP 850.1400) is the most frequently used bioassay for predicting chronic fish toxicity and supporting aquatic ecological risk assessments around the world. For each chemical, the FELS test req ...
Quantification of chemical toxicity continues to be generally based on measured external concentrations. Yet, internal chemical concentrations have been suggested to be a more suitable parameter. To better understand the relationship between the external a ...
Advances in food transformation have dramatically increased the diversity of products on the market and, consequently, exposed consumers to a complex spectrum of bioactive nutrients whose potential risks and benefits have mostly not been confidently demons ...
Mobile adaptive networks consist of a collection of nodes with learning and motion abilities that interact with each other locally in order to solve distributed processing and distributed inference problems in real-time. In this paper, we develop adaptatio ...
In the framework of a research project focusing on mitigation measures for hydropeaking, a lateral embayment at the channel bank is studied as a fish refuge. Systematic experiments with different refuge configurations were carried out. The basic configurat ...
Interstitial fluid flow has been shown to affect the organization and behavior of cells in 3D environments in vivo and in vitro, yet the forces driving such responses are not clear. Due to the complex architecture of the extracellular matrix (ECM) and the ...
In the framework of a research project focusing on mitigation measures for hydropeaking, a lateral embayment in riverbank is studied as a fish shelter. With the goal to find attractive configurations of shelter, systematic experiments with wild juvenile br ...