Decoding Neural Metabolic Markers From the Carotid Sinus Nerve in a Type 2 Diabetes Model
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Neuroprosthetics, the discipline that aims at interfacing neural systems to artificially engineered devices, has witnessed in recent years important advancements towards the ultimate goal of augmenting and restoring human functions through technology and a ...
Neuroprosthetic systems are designed to interface with the nervous system, for the replacement or restoration of damaged functions in the motor and/or sensory systems. In order to have an efficient communication with the nervous tissue leading to optimized ...
Diabetes type 2 patients are insensitive to insulin, a condition that leads to reduced glucose uptake by cells and, subsequently, to high concentration of glucose in the blood. For 60 years, biguanides have been one of the few effective therapeutics in red ...
Diabetes Type 1 is a metabolic disease which results in a lack of insulin production, causing high glucose levels in the blood. It is crucial for diabetic patients to balance this glucose level, and they depend on external substances to do so. In order to ...
Neuroprostheses based on electrical stimulation are becoming a therapeutic reality, dramatically improving the life of disabled people. They are based on neural interfaces that are designed to create an intimate contact with neural cells. These devices spe ...
Purpose Roux en Y gastric bypass surgery (RYGB) is an effective therapy for patients with severe obesity. It induces both significant weight loss and rapid improvements of metabolic complications. This study was undertaken to better define the direct role ...
In this paper, the problem of predicting blood glucose concentrations (BG) for the treatment of patients with type 1 diabetes, is addressed. Predicting BG is of very high importance as most treatments, which consist in exogenous insulin injections, rely on ...
The development of more effective approaches for controlling dexterous hand prostheses is an important area of research currently addressed by several groups with the aim of improving the quality of life of amputees. It is particularly important to establi ...
From epidemiological studies it is known that diabetes patients display increased risk of developing dementia. Moreover, cognitive impairment and Alzheimer's disease (AD) are also accompanied by impaired glucose homeostasis and insulin signalling. Although ...
To appreciate how neural circuits in the brain control behaviors, we must identify how the neurons comprising the circuit are connected. Neuronal connectivity is difficult to determine experimentally, whereas neuronal activity can often be readily measured ...