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Capillary flow device for bio-fluid collection with semiconductor sensors

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Microfluidic and Electrokinetic Manipulation of Single Cells

Samuel Kilchenmann

Traditional cell assays report on the average results of a cell population. However, a wide range of new tools are being developed for a fundamental understanding of single cell's functionality. Nonetheless, the current tools are either limited in their th ...

EPFL2017

During the last decades, the growing interest for single-cell analysis has led to the creation of a number of microfluidic and lab-on-a chip (LOC) platforms for characterizing cellular samples. In that context label-free based platforms are minimally invas ...

EPFL2016

Generating photocurrent by nanocomposites based on photosynthetic reaction centre protein

László Forró, Endre Horvath, Klara Hernadi, Emil Nyerki

An optoelectronic device, which converts light energy to electric potential, was designed and fabricated by using photosynthetic reaction centre (RC) proteins of purple bacterium Rhodobacter sphaeroides R-26, based on the structure and function of the dye ...

Wiley-V C H Verlag Gmbh2015

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Cell analysis requires increasingly more complex equipment to investigate cellular and molecular mechanisms. The goal of the present research is to develop a platform of integrated amperometric biosensors to better understand biological processes by real-t ...

2012

Improved Conversion Rates in Drug Screening Applications Using Miniaturized Electrochemical Cells with Frit Channels

Hubert Girault, Liang Qiao, Albert van den Berg

This paper reports a novel design of a miniaturized three-electrode electrochemical cell, the purpose of which is aimed at generating drug metabolites with a high conversion efficiency. The working electrode and the counter electrode are placed in two sepa ...

Amer Chemical Soc2012

Self-Assembled Liquid-Gated Zinc Oxide Nanowire Transistors

Vivek Pachauri

This thesis aims at the site-specific realization of self-assembled field-effect transistors (FETs) based on semiconducting Zinc oxide NWs and their application towards chemical and bio-sensing in liquid medium. At first, a solution based growth method for ...

EPFL2011

Chip cleaning and regeneration for electrochemical sensor arrays

Sandro Carrara, Bruno Samori

Sensing systems based on electrochemical detection have generated great interest because electronic readout may replace conventional optical readout in microarray. Moreover, they offer the possibility to avoid labelling for target molecules. A typical elec ...

Elsevier2010

Microfluidic Protein Preconcentrator Using a Microchannel-Integrated Nafion Strip: Experiment and Modeling

Martinus Gijs, Venkataragavalu Sivagnanam, Meng Shen

We propose a simple microfluidic device for protein preconcentration based on the electrokinetic trapping principle. It comprises a narrow Nafion strip that is simply cut from a commercial membrane and is integrated into a molded poly(dimethylsiloxane) (PD ...

American Chemical Society2010

A Novel Multi-Working Electrode Potentiostat for Electrochemical Detection of Metabolites

Giovanni De Micheli, Sandro Carrara, Cristina Boero, Michele Daniel Torre, Daniela De Venuto

A novel single-chip and multiplexed read-out circuit for multi-electrode electrochemical sensors, in standard 0.18 μm UMC CMOS technology, is presented. The circuit is a part of a fully-integrated biochip (in design) for the detection of multiple metabolit ...

2010

Rapid Prototyping of Microfluidic Devices

Meng Shen

With the growing importance of miniaturized energy applications and the development of micro Total Analysis Systems (μTAS), we have realized microfluidic devices, namely, magnetic micropumps, microfluidic fuel cells and membrane-based protein preconcentrat ...

EPFL2010