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In Silico Voltage-Sensitive Dye Imaging: A Model-Based Approach for Bridging Scales of Cortical Activity

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Neuronal Correlates of Tactile Working Memory in Prefrontal and Vibrissal Somatosensory Cortex

Vahid Esmaeili

Tactile working memory engages a broad network of cortical regions in primates. To assess whether the conclusions drawn from primates apply to rodents, we examined the vibrissal primary somatosensory cortex (vS1) and the prelimbic cortex (PL) in a delayed ...

2019

Detecting trends and further development potential of contemporary façade design for workspaces

Marilyne Andersen, Luisa Pastore

Façade design is claimed to fulfil a number of requirements in workplaces, ranging from privacy to safety and from comfort to aesthetics. For future R&D efforts in façade design, identifying the key drivers that should shape contemporary facades in office ...

2019

Membrane water for probing neuronal membrane potentials and ionic fluxes at the single cell level

Pierre Magistretti, Sylvie Roke, Orly Bagunu Tarun, Pascal Jourdain, Marie Eve Pascale Didier

Neurons communicate through electrochemical signaling within a complex network. These signals are composed of changes in membrane potentials and are traditionally measured with the aid of (toxic) fluorescent labels or invasive electrical probes. Here, we d ...

Nature Publishing Group2018

The human brain consists of approximately a hundred billion of neurons that communicate through a unique series of biochemical and electrical processes. When neuronal networks are solicited, electrochemical processes happen involving millions of cells with ...

EPFL2018

How does the brain process and memorize information? We all know that the neuron (also known as nerve cell) is the processing unit in the brain. But how do neurons work together in networks? The connectivity structure of neural networks plays an important ...

EPFL2017

Highly Dynamic Spatiotemporal Organization of Low-Frequency Activities During Behavioral States in the Mouse Cerebral Cortex

Sylvain Crochet, Pierre François Philippe Le Merre

Although low-frequency (LF < 10 Hz) activities have been considered as a hallmark of nonrapid eye movement (NREM) sleep, several studies have recently reported LF activities in the membrane potential of cortical neurons from different areas in awake mice. ...

Oxford University Press2017

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There have been few quantitative characterizations of the morphological, biophysical, and cable properties of neurons in the human neocortex. We employed feature-based statistical methods on a rare data set of 60 3D reconstructed pyramidal neurons from L2 ...

Oxford University Press2017

Microplastics as Vectors for Environmental Contaminants : Exploring Sorption, Desorption, and Transfer to Biota

Anders Meibom, Louise Helene Soegaard Jensen, Julia Marie Jeanne Yvonne Bodin, Philipp Mayer

The occurrence and effects of microplastics (MPs) in the aquatic environment are receiving increasing attention. In addition to their possible direct adverse effects on biota, the potential role of MPs as vectors for hydrophobic organic chemicals (HOCs), c ...

Society of Environmental Toxicology and Chemistry Press2017

The ability to control and modulate the action potential firing in neurons represents a powerful tool for neuroscience research and clinical applications. While neuronal excitation has been achieved with many tools, including electrical and optical stimula ...

2016

The ability to construct easily in vitro networks of primary neurons organized with imposed topologies is required for neural tissue engineering as well as for the development of neuronal interfaces with desirable characteristics. However, accumulating evi ...

Elsevier2016