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Diffusion MRI connectometry is a widely used tool to investigate features of structural connectomes that reflect differences in white matter tracks integrity. It consists in averaging microstructural tissues properties (obtained from any voxel-wise map) along streamlines recovered with diffusion tractography. Nevertheless, the average of a microstructural measure is a weak information about an entire bundle. Using microstructure-informed tractography (COMMIT), we were able to simultaneously estimate fiber’s specific myelin water fraction, intra-axonal volume fraction, and g-ratio. We also computed new connectomes with bundles’ specific measures instead of the commonly used averages.
Maria del Carmen Sandi Perez, Bogdan Draganski
Dimitri Nestor Alice Van De Ville, Elvira Pirondini, Cyprien Alban Félicien Rivier
Dimitri Nestor Alice Van De Ville, Friedhelm Christoph Hummel, Gabriel Girard, Takuya Morishita, Elena Beanato, Lisa Aïcha Mireille Julie Fleury, Maximilian Jonas Wessel, Philipp Johannes Koch, Philip Egger, Andéol Geoffroy Cadic-Melchior