Epidermal growth factor receptorThe epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). In many cancer types, mutations affecting EGFR expression or activity could result in cancer.
Sugar refineryA sugar refinery is a refinery which processes raw sugar from cane or sugar extracted from beets into white refined sugar. Cane sugar mills traditionally produce raw sugar, which is sugar that still contains molasses, giving it more colour (and impurities) than the white sugar which is normally consumed in households and used as an ingredient in soft drinks and foods. Raw cane sugar does not need refining to be palatable. It is refined for reasons such as health, color, and the requirement for a pure sugar taste.
Hearing protection fit-testingHearing protector fit-testing, also known as field attenuation estimation system (FAES), measures the degree of noise attenuation when using the hearing protection device by a particular worker in the enterprise. Such measurements are necessary because noise attenuation is very variable among workers, and it can be close to zero for a significant proportion of them. Individual anatomical differences and varying ability to correctly apply HPD do not allow predicting noise attenuation in workers based on laboratory measurements with satisfactory accuracy.
Grapefruit–drug interactionsSome fruit juices and fruits can interact with numerous drugs, in many cases causing adverse effects. The effect is most studied with grapefruit and grapefruit juice, but similar effects have been observed with certain other citrus fruits. The effect was first discovered accidentally in 1991, when a test of drug interactions with alcohol used grapefruit juice to hide the taste of the ethanol. A 2005 medical review advised patients to avoid all citrus juices until further research clarifies the risks.
GRB2Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2 protein is encoded by the GRB2 gene. The protein encoded by this gene binds receptors such as the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences.
Fully qualified domain nameA fully qualified domain name (FQDN), sometimes also referred to as an absolute domain name, is a domain name that specifies its exact location in the tree hierarchy of the Domain Name System (DNS). It specifies all domain levels, including the top-level domain and the root zone. A fully qualified domain name is distinguished by its lack of ambiguity in terms of DNS zone location in the hierarchy of DNS labels: it can be interpreted only in one way.
