Nuclear weapons of the United StatesThe United States was the first country to manufacture nuclear weapons and is the only country to have used them in combat, with the bombings of Hiroshima and Nagasaki in World War II. Before and during the Cold War, it conducted 1,054 nuclear tests, and tested many long-range nuclear weapons delivery systems. Between 1940 and 1996, the U.S. federal government spent at least US$ in present-day terms on nuclear weapons, including platforms development (aircraft, rockets and facilities), command and control, maintenance, waste management and administrative costs.
Droplet-based microfluidicsDroplet-based microfluidics manipulate discrete volumes of fluids in immiscible phases with low Reynolds number and laminar flow regimes. Interest in droplet-based microfluidics systems has been growing substantially in past decades. Microdroplets offer the feasibility of handling miniature volumes (μl to fl) of fluids conveniently, provide better mixing, encapsulation, sorting, sensing and are suitable for high throughput experiments.
Critical massIn nuclear engineering, a critical mass is the smallest amount of fissile material needed for a sustained nuclear chain reaction. The critical mass of a fissionable material depends upon its nuclear properties (specifically, its nuclear fission cross-section), density, shape, enrichment, purity, temperature, and surroundings. The concept is important in nuclear weapon design. When a nuclear chain reaction in a mass of fissile material is self-sustaining, the mass is said to be in a critical state in which there is no increase or decrease in power, temperature, or neutron population.
Axonal transportAxonal transport, also called axoplasmic transport or axoplasmic flow, is a cellular process responsible for movement of mitochondria, lipids, synaptic vesicles, proteins, and other organelles to and from a neuron's cell body, through the cytoplasm of its axon called the axoplasm. Since some axons are on the order of meters long, neurons cannot rely on diffusion to carry products of the nucleus and organelles to the end of their axons.
DynactinDynactin is a 23 subunit protein complex that acts as a co-factor for the microtubule motor cytoplasmic dynein-1. It is built around a short filament of actin related protein-1 (Arp1). Dynactin was identified as an activity that allowed purified cytoplasmic dynein to move membrane vesicles along microtubules in vitro. It was shown to be a multiprotein complex and named "dynactin" because of its role in dynein activation. The main features of dynactin were visualized by quick-freeze, deep-etch, rotary shadow electron microscopy.
Domain (biology)In biological taxonomy, a domain (dəˈmeɪn or doʊˈmeɪn) (Latin: regio), also dominion, superkingdom, realm, or empire, is the highest taxonomic rank of all organisms taken together. It was introduced in the three-domain system of taxonomy devised by Carl Woese, Otto Kandler and Mark Wheelis in 1990. According to the domain system, the tree of life consists of either three domains such as Archaea, Bacteria, and Eukarya, or two domains consisting of Archaea and Bacteria, with Eukarya included in Archaea.
Three-domain systemThe three-domain system is a biological classification introduced by Carl Woese, Otto Kandler, and Mark Wheelis in 1990 that divides cellular life forms into three domains, namely Archaea, Bacteria, and Eukaryota. The key difference from earlier classifications such as the two-empire system and the five-kingdom classification is the splitting of Archaea from bacteria as completely different organisms. It has been challenged by the two-domain system that divides organisms into Bacteria and Archaea only, as Eukaryotes are considered as one group of Archaea.
Nuclear bodiesNuclear bodies (also known as nuclear domains, or nuclear dots) are membraneless structures found in the cell nuclei of eukaryotic cells. Nuclear bodies include Cajal bodies, the nucleolus, and promyelocytic leukemia protein (PML) nuclear bodies (also called PML oncogenic dots). Nuclear bodies also include ND10s. ND stands for nuclear domain, and 10 refers to the number of dots seen.
