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Innovative Techniques and Strategies for a Reliable High-Throughput Genotoxicity Assessment
Related publications (32)
Risk prediction of developing venous thrombosis in combined oral contraceptive users
Emmanuelle Logette, Valérie Buchillier
Background Venous thromboembolism (VTE) is a complex multifactorial disease influenced by genetic and environmental risk factors. An example for the latter is the regular use of combined oral contraceptives (CC), which increases the risk to develop VTE by ...
2017Altitude: architecture et environnement de haute montagne
At the centre of the research is the preservation of the countryside which is highlighted and studied through an architectural approach which focuses on cabins in the high mountains. The projects must reflect upon territorial, global and sustainable aspect ...
EPFL2016Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: I. Challenges and research needs in ecotoxicology
To elucidate the effects of chemicals on populations of different species in the environment, efficient testing and modeling approaches are needed that consider multiple stressors and allow reliable extrapolation of responses across species. An adverse out ...
Pergamon-Elsevier Science Ltd2015Time-Lapse AFM Imaging of DNA Conformational Changes Induced by Daunorubicin
Giovanni Dietler, Sandor Kasas, Giovanni Longo, Livan Bladimir Alonso Sarduy
Cancer is a major health issue that absorbs the attention of a large part of the biomedical research. Intercalating agents bind to DNA molecules and can inhibit their synthesis and transcription; thus, they are increasingly used as drugs to fight cancer. I ...
American Chemical Society2013Expert Judgements in Risk Analysis: a Strategy to Overcome Uncertainities
Thierry Meyer, Amela Groso, David Nicolas Plüss
There is a need for a risk analysis technique specific for academic research laboratories. Since accurate accident data, normally required for quantitative risk analysis, are not available for this environment, expert judgements are often used to describe ...
2013Review and Advances in Methodologies for Rockfall Hazard and Risk Assessment
Vincent Labiouse, Jacopo Maria Abbruzzese
This section reviews the current methodologies that are used for the assessment of the rockfall susceptibility, hazard and risk. Emphasis is given on quantitative methods although qualitative ones are also discussed. The different methodologies are present ...
Springer2013Dynamics and environmental risk assessment of the herbicide glyphosate and its metabolite AMPA in a small vineyard river of the Lake Geneva catchment
The use of pesticides may lead to environmental problems, such as surface water pollution, with a risk for aquatic organisms. In the present study, a typical vineyard river of western Switzerland was first monitored to measure discharged loads, identify so ...
Wiley-Blackwell2013Risk analysis in research environment - Part I: Modeling Lab Criticity Index using Improved Risk Priority Number
Thierry Meyer, Amela Groso, Aristide Ramondgwendé Ouédraogo
Current available risk analysis techniques are well adapted to industry needs since they were developed for its purpose. All hazards present in industry are also met in research/academia, although quantities of some hazardous substances are smaller. Still, ...
2011Occurrence and fate of micropollutants in the Vidy Bay of Lake Geneva, part I: Priority list for environmental risk assessment of pharmaceuticals
Abstract—Pharmaceuticals are substances designed to have a biological effect in humans. Their presence in the environment, especially in surface waters, is of increasing concern because of their potential risk to non-target species. A large number of pharm ...
Society of Environmental Toxicology and Chemistry Press2010Comparison of two rock fall hazard mapping methodologies based on the French and Swiss guidelines
Vincent Labiouse, Jacopo Maria Abbruzzese
Landslide hazard mapping aims at providing very useful information for urban planning and for risk analysis. Though landslide risks represent a common threat to human lives and properties worldwide, the procedures applied for hazard and risk assessment are ...
2010